M. Matilde Marques

Papers authored by M. Matilde Marques

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2013 Aline T. Marinho, Patrícia M. Rodrigues, Umbelina Caixas, Alexandra M. M. Antunes, Teresa Branco, Shrika G. Harjivan, M. Matilde Marques

, Emília C. Monteiro, Sofia A. Pereira

Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions

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J. P. Miranda

, P. F. Pinheiro, A. T. Marinho, S. G. Harjivan, M. Castro, S. A. Pereira, A. M. M. Antunes, M. M. Marques

3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity

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Edson Dos A. Dos Santos, Ernest Hamel, Ruoli Bai, James C. Burnett, Camila Santos Suniga Tozatti, Danielle Bogo, Renata T. Perdomo, Alexandra M. M. Antunes, M. Matilde Marques

, Maria de F. C. Matos, Dênis P. de Lima

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

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Nádia M. Grilo, Alexandra M. M. Antunes, Umbelina Caixas, Aline T. Marinho, Catarina Charneira, M. Conceição Oliveira, Mc Oliveira, Emília C. Monteiro, M. Matilde Marques

, Sofia A. Pereira

Monitoring abacavir bioactivation in humans: Screening for an aldehyde metabolite

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Alexandra M. M. Antunes, Benjamin Wolf, M. Conceição Oliveira, M. Oliveira, Frederick A. Beland, M. Matilde Marques

2 '-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

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N. M. Grilo, A. M. M. Antunes, U. Caixas, A. T. Marinho, C. Charneira, S. Gouveia, M. C. Oliveira, M. M. Marques

, E. C. Monteiro, S. A. Pereira, A. Zarzuelo, R. Jimenez

Evidence of haptenation upon bioactivation of the anti-HIV drug abacavir to a reactive aldehyde in vivo

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A. T. Marinho, A. M. M. Antunes, U. Caixas, T. Branco, A. L. A. Godinho, M. C. Oliveira, M. M. Marques

, E. C. Monteiro, S. A. Pereira, A. Zarzuelo, R. Jimenez

Haptenation of the antiretroviral drug nevirapine upon bioactivation in man

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Frederick A. Beland, Paul W. Mellick, Greg R. Olson, Maria C. B. Mendoza, M. Matilde Marques

, Daniel R. Doerge

Carcinogenicity of acrylamide in B6C3F1 mice and F344/N rats from a 2-year drinking water exposure

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2012 Umbelina Caixas, Alexandra M. M. Antunes, Aline T. Marinho, Ana L. A. Godinho, Nádia M. Grilo, M. Matilde Marques

, Mc Conceição Oliveira, Teresa Branco, Emília C. Monteiro, Sofia A. Pereira

Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity

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Filipa Siopa, Alice S. Pereira, Luísa M. Ferreira

, M. Matilde Marques

, Paula S. Branco

Synthesis of catecholamine conjugates with nitrogen-centered bionucleophiles

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Linda S. Von Tungeln, Daniel R. Doerge, Gonçalo Gamboa da Costa, M. Matilde Marques

, William M. Witt, Igor Koturbash, Igor P. Pogribny, Frederick A. Beland

Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay

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Alexandra M. M. Antunes, Muna Sidarus, David A. Novais, Shrika G. Harjivan, Pedro P. Santos, João L. Ferreira da Silva, Frederick A. Beland, M. Matilde Marques

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction

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Riccardo Wanke, David A. Novais, Shrika G. Harjivan, M. Matilde Marques

, Alexandra M. M. Antunes

Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz

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Sofia A. Pereira, Riccardo Wanke, M. Matilde Marques

, Emília C. Monteiro, Alexandra M. M. Antunes

Insights into the Role of Bioactivation Mechanisms in the Toxic Events Elicited by Non-nucleoside Reverse Transcriptase Inhibitors

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2011 Catarina Charneira, Ana L. A. Godinho, M. Conceição Oliveira, Sofia A. Pereira, Emília C. Monteiro, M. Matilde Marques

, Alexandra M. M. Antunes

Reactive Aldehyde Metabolites from the Anti-HIV Drug Abacavir: Amino Acid Adducts as Possible Factors in Abacavir Toxicity

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Goncalo C. Justino, Shrika G. Harjivan, M. Matilde Marques

Metallocene derivatives as selective estrogen receptor modulators a computational docking to estrogen receptors a and b

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Alexandra M. M. Antunes, Goncalo C. Justino, Ines L. Martins, Catarina R. Charneira, M. Matilde Marques

Computational assessment of the potential role of chalcogenated flavonoids as antioxidants, enzyme inhibitors and cell signalling modulators via computational analysis

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J. L. Ferreira da Silva, André P. Ferreira, M. Matilde Marques

, Shrika G. Harjivan, M. Fátima M. da Piedade, M. Teresa Duarte

Effect of C–H…X interactions (X = O, S, π) in the supramolecular arrangements of 3-ferrocenyl-methoxybenzo[b]thiophene isomers

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Alexandra M. M. Antunes, David A. Novais, J. L. Ferreira da Silva, Pedro P. Santos, M. Conceição Oliveira, Frederick A. Beland, M. Matilde Marques

Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine

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Alexandra M. M. Antunes, Ana L. A. Godinho, Sofia A. Pereira, Gordon Surratt, Goncalo Gamboa da Costa, Frederick A. Beland, M. Matilde Marques

Nevirapine metabolism to 4-formyl-nevirapine: Possible role in nevirapine toxicity

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Papers authored by M. Matilde Marques