Manuela Garcia Lopez

Papers authored by Manuela Garcia Lopez

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2012 Silvia Lorrio, Vanessa Gómez-Rangel, Pilar Negredo

, Javier Egea, Rafael Leon, Alejandro Romero, Tharine Dal-Cim, Mercedes Villarroya, Maria Isabel Rodriguez-Franco

, Santiago Conde, Mariana P. Arce, Jose María Roda, Antonio G. García, Manuela G. López

Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

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Tharine Dal-Cim, Simone Molz, Javier Egea, Esther Parada, Alejandro Romero, Josiane Budni, Maria D. Martín de Saavedra, Laura del Barrio, Carla I. Tasca, Manuela G. López

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

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L. González-Lafuente, J. Egea, R. León, F. J. Martínez-Sanz, L. Monjas, C. Perez, C. Merino, A. M. García-De Diego, M. I. Rodríguez-Franco, A. G. García, M. Villarroya, M. G. López

, C. De Los Ríos

Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry

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2011 Javier Egea, Eduardo Malmierca, Angelo O. Rosa, Laura del Barrio, Pilar Negredo

, Angel Nuñez

, Manuela G. López

Participation of calbindin-D28K in nociception: results from calbindin-D28K knockout mice

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J. Egea, Martín De-Saavedra, M. D. Martín de Saavedra, L. del Barrio, E. Parada, A. Romero, A. O. Rosa, A. G. García, M. G. López

Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation

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Josiane Budni, Kelly R. Lobato, Ricardo W. Binfaré, Andiara E. Freitas, Ana Paula Costa, Maria Dolores Martín-De-Saavedra, Rodrigo B. Leal

, Manuela G. Lopez

, Ana Lúcia S. Rodrigues

Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice

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Manuela Bartolini

, Marco Pistolozzi, Vincenza Andrisano, Javier Egea, Manuela G. López

, Isabel Iriepa, Ignacio Moraleda, Enrique Gálvez, José Marco-Contelles, Abdelouahid Samadi

Chemical and Pharmacological Studies on Enantiomerically Pure p‐Methoxytacripyrines, Promising Multi‐Target‐Directed Ligands for the Treatment of Alzheimer’s Disease

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Laura del Barrio, María Dolores Martín-De-Saavedra, Alejandro Romero, Esther Parada, Javier Egea, Jesús Avila, John Michael McIntosh, Susan Wonnacott, Manuela G. López

Neurotoxicity Induced by Okadaic Acid in the Human Neuroblastoma SH-SY5Y Line Can Be Differentially Prevented by α7 and β2* Nicotinic Stimulation

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Simone Molz, Tharine Dal-Cim, Josiane Budni, M. D. Martín de Saavedra, Javier Egea, Alejandro Romero, Laura del Barrio, Ana L. S. Rodrigues

, Manuela G. López

, Carla I. Tasca

Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition

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Daniel Silva, Cristóbal de Los Ríos, Mourad Chioua, Abdelouahid Samadi, M. Carmo Carreiras, María-Luisa Jimeno

, Eduarda Mendes, Cristóbal de los Ríos

, Alejandro Romero, Mercedes Villarroya, Manuela G. López

, José Marco-Contelles

Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives

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J. Budni, A. Romero, S. Molz, M. D. Martín de Saavedra, J. Egea, L. Del Barrio, C. I. Tasca, A. L. S. Rodrigues

, M. G. López

Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid

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Gema C. González Muñoz, Laura del Barrio, María Dolores Martín de-Saavedra, Mariana P. Arce, Beatriz López, Concepción Pérez, Alejandro Romero, Laura del Barrio, María Dolores Martín-De-Saavedra, Javier Egea, Rafael León, Mercedes Villarroya, Manuela G. López

, Antonio G. García, Santiago Conde and 1 other authors

N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease

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Daniel F. Martins, Angelo O. Rosa, Vinícius M. Gadotti, Leidiane Mazzardo-Martins, Francisney P. Nascimento, Javier Egea, Manuela G. López

, Adair R. S. Santos

The Antinociceptive Effects of AR-A014418, a Selective Inhibitor of Glycogen Synthase Kinase-3 Beta, in Mice

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María Dolores Martín-De-Saavedra, María Dolores Martín de-Saavedra, Laura del Barrio, Noelia Cañas, Javier Egea, Silvia Lorrio, Eulàlia Montell, Josep Vergés, Antonio G. García, Manuela G. López

Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS

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Abdelouahid Samadi, Cristóbal de los Ríos, Carolina Valderas, Cristóbal de los Ríos

, Agatha Bastida

, Mourad Chioua, Laura González-Lafuente, Inés Colmena, Luis Gandía

, Alejandro Romero, Laura del Barrio, Laura Del Barrio, María D. Martín de Saavedra, Manuela G. López

, Mercedes Villarroya and 1 other authors

Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles

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2010 Laura Del Barrio, Javier Egea, Rafael León, Alejandro Romero, Ana Ruiz, Mayte Montero, Javier Álvarez, Javier Alvarez, Manuela G. López

Calcium signalling mediated through a7 and non-a7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release

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Esther Parada, Javier Egea, Alejandro Romero, Laura del Barrio, Antonio G. García, Manuela G. López

Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via α7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway

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Gema C. González Muñoz, Mariana P. Arce, Beatriz López, Concepción Pérez, Mercedes Villarroya, Manuela G. López

, Antonio G. García, Santiago Conde, María Isabel Rodríguez-Franco

Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases

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Santos M. Nicolau, Javier Egea, Manuela G. López

, Antonio G. García

Mitochondrial Na+/Ca2+ exchanger, a new target for neuroprotection in rat hippocampal slices

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Abdelouahid Samadi, José Marco-Contelles, Elena Soriano, Mónica Álvarez-Pérez

, Mónica Alvarez-Pérez, Mourad Chioua, Alejandro Romero, Laura González-Lafuente, Luis Gandía

, José M. Roda, Manuela G. López

, Mercedes Villarroya, Antonio G. García, Cristóbal de los Ríos

, Cristóbal de Los Ríos

Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles

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Papers authored by Manuela Garcia Lopez