Douglas Mitchell - Dissemin

All papers authored by Douglas Mitchell

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2018 Julian D. Hegemann

, Christopher J. Schwalen, Douglas A. Mitchell

, Wilfred A. van der Donk

Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin

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2015 Graham A. Hudson, Zhengan Zhang, Jonathan I. Tietz, Douglas A. Mitchell

, Wilfred A. van der Donk

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin

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Tucker Maxson, Jeffery A. Bertke, Danielle L. Gray, Douglas A. Mitchell

Crystal structure and absolute configuration of (3S,4aS,8aS)-N-tert-butyl-2-[(S)-3-(2-chloro-4-nitrobenzamido)-2-hydroxypropyl]decahydroisoquinoline-3-carboxamide and (3S,4aS,8aS)-N-tert-butyl-2-{(S)-2-[(S)-1-(2-chloro-4-nitrobenzoyl)pyrrolidin-2-yl]-2-hydroxyethyl}decahydroisoquinoline-3-carboxamide

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Courtney L. Cox, James R. Doroghazi, Douglas A. Mitchell

The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles

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Jonathan I. Tietz, Douglas A. Mitchell

Using Genomics for Natural Product Structure Elucidation

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Tucker Maxson, Douglas A. Mitchell

Targeted treatment for bacterial infections: prospects for pathogen-specific antibiotics coupled with rapid diagnostics

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Molloy Em, Casjens Sr, Ethridge Na, Evelyn M. Molloy, Sherwood R. Casjens, Courtney L. Cox, Cox Cl, Tucker Maxson, Nicole A. Ethridge, Gabriele Margos, Volker Fingerle, Mitchell Da, Douglas A. Mitchell

Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family

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Brandon J. Burkhart, Graham A. Hudson, Kyle L. Dunbar, Douglas A. Mitchell

A prevalent peptide-binding domain guides ribosomal natural product biosynthesis

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Kyle L. Dunbar, Jonathan I. Tietz, Courtney L. Cox, Brandon J. Burkhart, Douglas A. Mitchell

Identification of an Auxiliary Leader Peptide-Binding Protein Required for Azoline Formation in Ribosomal Natural Products

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Tucker Maxson, Caitlin D. Deane, Evelyn M. Molloy, Courtney L. Cox, Andrew L. Markley, Shaun W. Lee, Douglas A. Mitchell

HIV Protease Inhibitors Block Streptolysin S Production

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Yue Hao, Patricia M. Blair, Abhishek Sharma, Douglas A. Mitchell

, Satish K. Nair

Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin

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Mikhail Metelev

, Jonathan I. Tietz, Joel O. Melby, Patricia M. Blair, Lingyang Zhu, Itamar Livnat, Konstantin Severinov, Douglas A. Mitchell

Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete

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Marnix H. Medema, Renzo Kottmann, Yi Yilmaz, Medema Mh, Pelin Yilmaz

, Matthew Cummings, John B. Biggins, Kai Blin

, Biggins Jb, Irene de Bruijn

, I. De Bruijn, Yit Heng Chooi, Jan Claesen, Chooi Yh, R. Cameron Coates and 228 other authors

Minimum Information about a Biosynthetic Gene cluster.

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2014 Kyle L. Dunbar, Jonathan R. Chekan, Courtney L. Cox, Brandon J. Burkhart, Satish K. Nair, Douglas A. Mitchell

Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis

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Courtney L. Cox, Jonathan I. Tietz, Karol Sokolowski, Joel O. Melby, James R. Doroghazi, Douglas A. Mitchell

Nucleophilic 1,4-Additions for Natural Product Discovery

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William Sinko, Yang Wang, Wei Zhu, Yonghui Zhang, Ferran Feixas, Courtney L. Cox, Douglas A. Mitchell

, Eric Oldfield, J. Andrew McCammon, J. Andrew McCammon

Undecaprenyl Diphosphate Synthase Inhibitors: Antibacterial Drug Leads

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Kai Li, Lici A. Schurig-Briccio, Xinxin Feng, Ashutosh Upadhyay, Venugopal Pujari, Benoit Lechartier, Fabio L. Fontes, Hongliang Yang, Guodong Rao, Wei Zhu, Anmol Gulati, Joo Hwan No, Giovana Cintra, Shannon Bogue, Yi-Liang Liu and 13 other authors

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

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Joel O. Melby, Xiangpo Li, Douglas A. Mitchell

Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases

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2013 Caitlin D. Deane, Douglas A. Mitchell

Lessons learned from the transformation of natural product discovery to a genome-driven endeavor

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Abhishek Sharma, Patricia M. Blair, Douglas A. Mitchell

Synthesis of Plantazolicin Analogues Enables Dissection of Ligand Binding Interactions of a Highly Selective Methyltransferase

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All papers authored by Douglas Mitchell