Dik C. van Gent - Dissemin

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All papers authored by Dik C. van Gent

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2021 Sanjiban Chakrabarty

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, William F. Quiros-Solano, Maayke M. P. Kuijten, Ben Haspels

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, Sandeep Mallya, Calvin Shun Yu Lo, Amr Othman, Cinzia Silvestri

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, Anja van de Stolpe

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, Nikolas Gaio, Hanny Odijk, Marieke van de Ven

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, Corrina M. A. de Ridder, Wytske M. van Weerden

ORCID

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and 4 other authors

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture

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Emilia M. Pulver

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, Pulver Em, Chirantani Mukherjee

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, Stefan J. Roobol

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, Gerarda van de Kamp, Magdalena B. Rother, Maria Valeria Lattanzio, Roobol Sj, Hanneke van der Gulden, Anne Paulien Drenth, Rother Mb, Roebi de Bruijn, Nicole S. Verkaik, Kerstin Hahn, Sjoerd Klarenbeek

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and 15 other authors

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

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Elena Bonora, Sanjiban Chakrabarty

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, Georgios Kellaris, Makiko Tsutsumi, Francesca Bianco, Christian Bergamini, Farid Ullah, Federica Isidori, Irene Liparulo

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, Chiara Diquigiovanni, Luca Masin, Nicola Rizzardi, Mariapia Giuditta Cratere, Elisa Boschetti, Valentina Papa and 52 other authors

Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy

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2020 Lise M. van Wijk

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, Sylvia Vermeulen, Matty Meijers, Manuela F. van Diest

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, Natalja T. ter Haar, Marthe M. de Jonge

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, Nienke Solleveld-Westerink, Tom van Wezel

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, Dik C. van Gent

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, Judith R. Kroep, Tjalling Bosse, Katja N. Gaarenstroom, Harry Vrieling, Maaike P. G. Vreeswijk

ORCID

The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas

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Takabumi Inagawa, Thomas Wennink, Joyce H. G. Lebbink, Guido Keijzers

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, Bogdan I. Florea

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, Nicole S. Verkaik, Dik C. van Gent

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C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties

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Chinmoy Saha

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, Prarthana Mohanraju

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, Andrew Stubbs

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, Youri Hoogstrate

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, Gert-Jan Kremers

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, Wiggert A. van Cappellen, Deborah Horst-Kreft, Charlie Laffeber, Joyce H. G. Lebbink, Serena Bruens, Duncan Gaskin, Dior Beerens, Maarten Klunder, Rob Joosten and 7 other authors

Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA

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Alex N. Zelensky

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, Mascha Schoonakker, Inger Brandsma

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, Marcel Tijsterman

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, Dik C. van Gent

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, Jeroen Essers, Roland Kanaar

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Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner

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2018 Titia G. Meijer, Nicole S. Verkaik, Anieta M. Sieuwerts

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ORCID

, Kishan A. T. Naipal, Carolien H. M. van Deurzen, Michael A. den Bakker, Hein F. B. M. Sleddens, Hendrikus-Jan Dubbink, T. Dorine den Toom, Winand N. M. Dinjens, Esther H. Lips, Petra M. Nederlof

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, Marcel Smid, Harmen J. G. van de Werken

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and 4 other authors

Functional ex vivo assay reveals homologous recombination deficiency in breast cancer beyond BRCA gene defects

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2016 H. (Hanna) IJspeert, D. van Zessen

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, J. (Jacob) Rozmus, K. (Klaus) Schwarz, René L. (René L.) Warren, D. (David) van Zessen, R. van der Holt, Robert A. Holt, I. (Ingrid) Pico-Knijnenburg, Erik J. (Erik J.) Simons, I. (Isabel) Jerchel, A. (Angela) Wawer, M. (Myriam) Lorenz, T. Pat ro lu, T. (Turkan) Patiroglu and 9 other authors

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination

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Kristell L. S. Chatalic, Chatalic Kls, Mark Konijnenberg, Julie Nonnekens, Erik de Blois, Sander Hoeben, Dik C. van Gent

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, Corrina de Ridder, Luc Brunel, Wytske M. van Weerden, Jean-Alain Fehrentz, Fehrentz Ja, Jean Martinez, van Gent Dc, Berthold A. Nock and 4 other authors

In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies

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2015 Kishan A. T. Naipal, Nicole S. Verkaik, Serena T. Bruens, Anja Raams, Geert J. L. H. van Leenders, Inger Brandsma, Nicolaas G. J. Jaspers, Dik C. van Gent

ORCID

, Jan H. J. Hoeijmakers, Joost L. Boormans, G. J. L. H. Van Leenders, Joris Pothof, Roland Kanaar, D. C. Van Gent

Attenuated XPC Expression Is Not Associated with Impaired DNA Repair in Bladder Cancer

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Bram van den Broek

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, Guotai Xu, Iris de Rink, Jorma de Ronde, Dik C. van Gent

ORCID

, J. Ross Chapman, J. Ross Chapman, Chapman Jr, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Janneke E. Jaspers, Ariena Kersbergen, Ewa Gogola, Wendy Sol and 18 other authors

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

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2013 Elin Enervald, E. Enervald (Elin), Likun Du, L. Du (Likun), Torkild Visnes

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, T. Visnes (Torkild), Andrea Björkman, A. Björkman (Andrea), Emma Lindgren, E. Lindgren (Emma), Josephine Wincent, J. Wincent (Josephine), Guntram Borck, H. Göbel (Hartmut), Laurence Colleaux

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and 20 other authors

A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination

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2012 Inger Brandsma, Dik C. Gent

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Pathway choice in DNA double strand break repair: observations of a balancing act

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2011 Michal Malewicz, Banafsheh Kadkhodaei, Nigel Kee, Nikolaos Volakakis, Ulf Hellman, Kristina Viktorsson, Chuen Yan Leung, Benjamin Chen, Rolf Lewensohn, Dik C. van Gent

ORCID

, David J. Chen, Thomas Perlmann

Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair

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2009 Linda Brugmans, Nicole S. Verkaik, Maurice Kunen, Ellen van Drunen, Bret R. Williams

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, John H. J. Petrini, Roland Kanaar, Jeroen Essers, Dik C. van Gent

ORCID

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication

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2008 Eric Weterings, Nicole S. Verkaik, Guido Keijzers

ORCID

, Bogdan I. Florea, Shih-Ya Wang, Laura G. Ortega, Naoya Uematsu, David J. Chen, Dik C. van Gent

ORCID

The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends

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Mirjam van der Burg, Hanna IJspeert, Nicole S. Verkaik, Tuba Turul, Wouter W. Wiegant, Keiko Morotomi-Yano, Pierre-Olivier Mari, Ilhan Tezcan, David J. Chen, Malgorzata Z. Zdzienicka, Jacques J. M. van Dongen

ORCID

, Dik C. van Gent

ORCID

A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining

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2006 Pierre-Olivier Mari, Bogdan I. Florea

ORCID

, Stephan P. Persengiev, Nicole S. Verkaik, Hennie T. Brüggenwirth, Mauro Modesti, Giuseppina Giglia-Mari, Karel Bezstarosti, Jeroen A. A. Demmers, Theo M. Luider, Adriaan B. Houtsmuller, Dik C. van Gent

ORCID

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

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2005 Koji Kikuchi, K. Kikuchi (Koji), Yoshihito Taniguchi, H. Koyama (Hideki), Atsushi Hatanaka, M. Jasin (Maria), Eiichiro Sonoda, Helfrid Hochegger

ORCID

, S. Takeda (Shiunichi), Noritaka Adachi, Y. Taniguchi (Yoshihito), Yasuo Matsuzaki, A. Hatanaka (Atsushi), Hideki Koyama, E. Sonoda (Eiichiro) and 5 other authors

Fen-1 Facilitates Homologous Recombination by Removing Divergent Sequences at DNA Break Ends†

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