All papers authored by Costas Lyssiotis
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2023
Matthew H. Ward 
,
Zeribe C. Nwosu,
Costas A. Lyssiotis
,
Zeribe C. Nwosu,
Costas A. Lyssiotis
Uridine: as sweet as sugar for some cells?
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Zeribe C. Nwosu ,
Matthew H. Ward ,
Peter Sajjakulnukit ,
Pawan Poudel,
Chanthirika Ragulan,
Steven Kasperek ,
Megan Radyk,
Damien Sutton,
Rosa E. Menjivar,
Anthony Andren,
Juan J. Apiz-Saab,
Zachary Tolstyka,
Kristee Brown,
Ho-Joon Lee ,
Lindsey N. Dzierozynski
and 14 other authors
,
Matthew H. Ward ,
Peter Sajjakulnukit ,
Pawan Poudel,
Chanthirika Ragulan,
Steven Kasperek ,
Megan Radyk,
Damien Sutton,
Rosa E. Menjivar,
Anthony Andren,
Juan J. Apiz-Saab,
Zachary Tolstyka,
Kristee Brown,
Ho-Joon Lee ,
Lindsey N. Dzierozynski
and 14 other authors
Uridine-derived ribose fuels glucose-restricted pancreatic cancer
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Ziheng Chen ,
I.-Lin Ho,
Melinda Soeung ,
Er-Yen Yen ,
Jintan Liu ,
Liang Yan,
Johnathon L. Rose,
Sanjana Srinivasan,
Shan Jiang,
Q. Edward Chang,
Ningping Feng,
Jason P. Gay,
Qi Wang ,
Jing Wang ,
Philip L. Lorenzi
and 12 other authors
,
I.-Lin Ho,
Melinda Soeung ,
Er-Yen Yen ,
Jintan Liu ,
Liang Yan,
Johnathon L. Rose,
Sanjana Srinivasan,
Shan Jiang,
Q. Edward Chang,
Ningping Feng,
Jason P. Gay,
Qi Wang ,
Jing Wang ,
Philip L. Lorenzi
and 12 other authors
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis
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2022
Christopher J. Halbrook ,
Galloway Thurston,
Seth Boyer,
Cecily Anaraki,
Jennifer A. Jiménez,
Amy McCarthy,
Nina G. Steele,
Samuel A. Kerk ,
Hanna S. Hong ,
Lin Lin,
Fiona V. Law,
Catherine Felton,
Lorenzo Scipioni,
Peter Sajjakulnukit ,
Anthony Andren
and 19 other authors
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,
Galloway Thurston,
Seth Boyer,
Cecily Anaraki,
Jennifer A. Jiménez,
Amy McCarthy,
Nina G. Steele,
Samuel A. Kerk ,
Hanna S. Hong ,
Lin Lin,
Fiona V. Law,
Catherine Felton,
Lorenzo Scipioni,
Peter Sajjakulnukit ,
Anthony Andren
and 19 other authors
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Samuel A. Kerk ,
Lin Lin,
Amy L. Myers,
Damien J. Sutton,
Anthony Andren,
Peter Sajjakulnukit,
Li Zhang,
Yaqing Zhang,
Jennifer A. Jiménez,
Barbara S. Nelson,
Brandon Chen,
Anthony Robinson,
Galloway Thurston,
Samantha B. Kemp,
Nina G. Steele
and 16 other authors
,
Lin Lin,
Amy L. Myers,
Damien J. Sutton,
Anthony Andren,
Peter Sajjakulnukit,
Li Zhang,
Yaqing Zhang,
Jennifer A. Jiménez,
Barbara S. Nelson,
Brandon Chen,
Anthony Robinson,
Galloway Thurston,
Samantha B. Kemp,
Nina G. Steele
and 16 other authors
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context
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Seth Boyer,
Ho-Joon Lee ,
Nina Steele,
Li Zhang,
Peter Sajjakulnukit,
Anthony Andren,
Matthew H. Ward ,
Rima Singh ,
Venkatesha Basrur,
Yaqing Zhang,
Alexey I. Nesvizhskii,
Marina Pasca di Magliano,
Christopher J. Halbrook ,
Costas A. Lyssiotis
Download from doi.org
,
Nina Steele,
Li Zhang,
Peter Sajjakulnukit,
Anthony Andren,
Matthew H. Ward ,
Rima Singh ,
Venkatesha Basrur,
Yaqing Zhang,
Alexey I. Nesvizhskii,
Marina Pasca di Magliano,
Christopher J. Halbrook ,
Costas A. Lyssiotis
Download from doi.org
Hannah N. Bell,
Ryan J. Rebernick ,
Joshua Goyert ,
Rashi Singhal,
Miljan Kuljanin,
Samuel A. Kerk,
Wesley Huang ,
Nupur K. Das ,
Anthony Andren,
Sumeet Solanki,
Shannon L. Miller,
Peter K. Todd,
Eric R. Fearon ,
Costas A. Lyssiotis ,
Steven P. Gygi
and 2 other authors
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,
Joshua Goyert ,
Rashi Singhal,
Miljan Kuljanin,
Samuel A. Kerk,
Wesley Huang ,
Nupur K. Das ,
Anthony Andren,
Sumeet Solanki,
Shannon L. Miller,
Peter K. Todd,
Eric R. Fearon ,
Costas A. Lyssiotis ,
Steven P. Gygi
and 2 other authors
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2021
Daniel M. Kremer ,
Barbara S. Nelson,
Lin Lin,
Emily L. Yarosz ,
Christopher J. Halbrook ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Amy Myers,
Galloway Thurston,
Sean W. Hou,
Eileen S. Carpenter,
Anthony C. Andren,
Zeribe C. Nwosu ,
Nicholas Cusmano,
Stephanie Wisner
and 19 other authors
,
Barbara S. Nelson,
Lin Lin,
Emily L. Yarosz ,
Christopher J. Halbrook ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Amy Myers,
Galloway Thurston,
Sean W. Hou,
Eileen S. Carpenter,
Anthony C. Andren,
Zeribe C. Nwosu ,
Nicholas Cusmano,
Stephanie Wisner
and 19 other authors
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
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Andrew J. Schwartz,
Joshua W. Goyert ,
Sumeet Solanki,
Samuel A. Kerk ,
Brandon Chen ,
Cristina Castillo,
Peggy P. Hsu,
Brian T. Do ,
Rashi Singhal ,
Michael K. Dame ,
Ho-Joon Lee ,
Jason R. Spence,
Samira Lakhal-Littleton,
Matthew G. Vander Heiden ,
Costas A. Lyssiotis
and 2 other authors
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,
Sumeet Solanki,
Samuel A. Kerk ,
Brandon Chen ,
Cristina Castillo,
Peggy P. Hsu,
Brian T. Do ,
Rashi Singhal ,
Michael K. Dame ,
Ho-Joon Lee ,
Jason R. Spence,
Samira Lakhal-Littleton,
Matthew G. Vander Heiden ,
Costas A. Lyssiotis
and 2 other authors
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Samantha N. Devenport,
Rashi Singhal ,
Megan D. Radyk,
Joseph G. Taranto ,
Samuel A. Kerk ,
Brandon Chen ,
Joshua W. Goyert ,
Chesta Jain,
Nupur K. Das ,
Katherine Oravecz-Wilson,
Li Zhang,
Joel K. Greenson,
Y. Eugene Chen ,
Scott A. Soleimanpour ,
Pavan Reddy
and 2 other authors
Download from doi.org
,
Megan D. Radyk,
Joseph G. Taranto ,
Samuel A. Kerk ,
Brandon Chen ,
Joshua W. Goyert ,
Chesta Jain,
Nupur K. Das ,
Katherine Oravecz-Wilson,
Li Zhang,
Joel K. Greenson,
Y. Eugene Chen ,
Scott A. Soleimanpour ,
Pavan Reddy
and 2 other authors
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Rashi Singhal ,
Sreedhar R. Mitta,
Nupur K. Das ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Sumeet Solanki,
Anthony Andren ,
Roshan Kumar ,
Kenneth P. Olive ,
Ruma Banerjee ,
Costas A. Lyssiotis ,
Yatrik M. Shah
,
Sreedhar R. Mitta,
Nupur K. Das ,
Samuel A. Kerk ,
Peter Sajjakulnukit ,
Sumeet Solanki,
Anthony Andren ,
Roshan Kumar ,
Kenneth P. Olive ,
Ruma Banerjee ,
Costas A. Lyssiotis ,
Yatrik M. Shah
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron
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Samantha B. Kemp,
Eileen S. Carpenter,
Nina G. Steele,
Katelyn L. Donahue ,
Zeribe C. Nwosu ,
Amanda Pacheco ,
Ashley Velez-Delgado,
Rosa E. Menjivar,
Fatima Lima,
Stephanie The,
Carlos E. Espinoza,
Kristee Brown,
Daniel Long,
Costas A. Lyssiotis ,
Arvind Rao
and 3 other authors
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,
Zeribe C. Nwosu ,
Amanda Pacheco ,
Ashley Velez-Delgado,
Rosa E. Menjivar,
Fatima Lima,
Stephanie The,
Carlos E. Espinoza,
Kristee Brown,
Daniel Long,
Costas A. Lyssiotis ,
Arvind Rao
and 3 other authors
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Francesca Puca,
Fei Yu,
Caterina Bartolacci ,
Piergiorgio Pettazzoni,
Alessandro Carugo ,
Emmet Huang-Hobbs ,
Jintan Liu ,
Ciro Zanca,
Federica Carbone ,
Edoardo Del Poggetto,
Joy Gumin,
Pushan Dasgupta ,
Sahil Seth ,
Sanjana Srinivasan,
Frederick F. Lang
and 14 other authors
,
Piergiorgio Pettazzoni,
Alessandro Carugo ,
Emmet Huang-Hobbs ,
Jintan Liu ,
Ciro Zanca,
Federica Carbone ,
Edoardo Del Poggetto,
Joy Gumin,
Pushan Dasgupta ,
Sahil Seth ,
Sanjana Srinivasan,
Frederick F. Lang
and 14 other authors
Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma
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Samantha B. Kemp,
Nina G. Steele,
Eileen S. Carpenter,
Katelyn L. Donahue,
Grace G. Bushnell,
Aaron H. Morris,
Stephanie The,
Sophia M. Orbach,
Veerin R. Sirihorachai,
Zeribe C. Nwosu ,
Carlos Espinoza,
Fatima Lima,
Kristee Brown,
Alexander A. Girgis ,
Valerie Gunchick
and 9 other authors
,
Carlos Espinoza,
Fatima Lima,
Kristee Brown,
Alexander A. Girgis ,
Valerie Gunchick
and 9 other authors
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages
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Jennifer A. Jiménez ,
April A. Apfelbaum ,
Allegra G. Hawkins,
Laurie K. Svoboda ,
Abhijay Kumar,
Ramon Ocadiz Ruiz ,
Alessandra X. Garcia,
Elena Haarer,
Zeribe C. Nwosu ,
Joshua Bradin ,
Trupta Purohit,
Dong Chen,
Tomasz Cierpicki,
Jolanta Grembecka,
Costas A. Lyssiotis
and 1 other authors
,
April A. Apfelbaum ,
Allegra G. Hawkins,
Laurie K. Svoboda ,
Abhijay Kumar,
Ramon Ocadiz Ruiz ,
Alessandra X. Garcia,
Elena Haarer,
Zeribe C. Nwosu ,
Joshua Bradin ,
Trupta Purohit,
Dong Chen,
Tomasz Cierpicki,
Jolanta Grembecka,
Costas A. Lyssiotis
and 1 other authors
EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma
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Nina G. Steele,
Giulia Biffi ,
Samantha B. Kemp,
Yaqing Zhang,
Donovan Drouillard,
Li-Jyun Syu,
Yuan Hao,
Tobiloba E. Oni,
Erin Brosnan,
Ela Elyada,
Abhishek Doshi ,
Christa Hansma,
Carlos Espinoza,
Ahmed Abbas,
Stephanie The
and 21 other authors
,
Samantha B. Kemp,
Yaqing Zhang,
Donovan Drouillard,
Li-Jyun Syu,
Yuan Hao,
Tobiloba E. Oni,
Erin Brosnan,
Ela Elyada,
Abhishek Doshi ,
Christa Hansma,
Carlos Espinoza,
Ahmed Abbas,
Stephanie The
and 21 other authors
Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer
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2020
Yingjie Bian ,
Wei Li,
Daniel M. Kremer ,
Peter Sajjakulnukit ,
Shasha Li,
Joel Crespo,
Zeribe C. Nwosu ,
Li Zhang,
Arkadiusz Czerwonka,
Anna Pawłowska ,
Houjun Xia,
Jing Li,
Peng Liao ,
Jiali Yu,
Linda Vatan
and 14 other authors
,
Wei Li,
Daniel M. Kremer ,
Peter Sajjakulnukit ,
Shasha Li,
Joel Crespo,
Zeribe C. Nwosu ,
Li Zhang,
Arkadiusz Czerwonka,
Anna Pawłowska ,
Houjun Xia,
Jing Li,
Peng Liao ,
Jiali Yu,
Linda Vatan
and 14 other authors
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
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