All papers authored by Matthew Hellmann
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2022
Kanika Arora 
,
Thinh N. Tran ,
Yelena Kemel ,
Miika Mehine ,
Ying L. Liu ,
Subhiksha Nandakumar ,
Shaleigh A. Smith ,
A. Rose Brannon ,
Irina Ostrovnaya ,
Konrad H. Stopsack ,
Pedram Razavi ,
Anton Safonov ,
Hira A. Rizvi ,
Matthew D. Hellmann ,
Joseph Vijai
and 13 other authors
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,
Thinh N. Tran ,
Yelena Kemel ,
Miika Mehine ,
Ying L. Liu ,
Subhiksha Nandakumar ,
Shaleigh A. Smith ,
A. Rose Brannon ,
Irina Ostrovnaya ,
Konrad H. Stopsack ,
Pedram Razavi ,
Anton Safonov ,
Hira A. Rizvi ,
Matthew D. Hellmann ,
Joseph Vijai
and 13 other authors
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Sara E. Schad ,
Andrew Chow ,
Levi Mangarin ,
Heng Pan ,
Jiajia Zhang ,
Nicholas Ceglia ,
Justina X. Caushi ,
Nicole Malandro ,
Roberta Zappasodi ,
Mathieu Gigoux ,
Daniel Hirschhorn ,
Sadna Budhu ,
Masataka Amisaki ,
Monica Arniella ,
David Redmond
and 11 other authors
,
Andrew Chow ,
Levi Mangarin ,
Heng Pan ,
Jiajia Zhang ,
Nicholas Ceglia ,
Justina X. Caushi ,
Nicole Malandro ,
Roberta Zappasodi ,
Mathieu Gigoux ,
Daniel Hirschhorn ,
Sadna Budhu ,
Masataka Amisaki ,
Monica Arniella ,
David Redmond
and 11 other authors
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions
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Semanti Mukherjee ,
Chaitanya Bandlamudi,
Matthew D. Hellmann ,
Yelena Kemel ,
Esther Drill ,
Hira Rizvi,
Kaitlyn Tkachuk,
Aliya Khurram,
Michael F. Walsh ,
Marjorie G. Zauderer ,
Diana Mandelker,
Sabine Topka,
Ahmet Zehir ,
Preethi Srinivasan,
Myvizhi Esai Selvan
and 22 other authors
,
Chaitanya Bandlamudi,
Matthew D. Hellmann ,
Yelena Kemel ,
Esther Drill ,
Hira Rizvi,
Kaitlyn Tkachuk,
Aliya Khurram,
Michael F. Walsh ,
Marjorie G. Zauderer ,
Diana Mandelker,
Sabine Topka,
Ahmet Zehir ,
Preethi Srinivasan,
Myvizhi Esai Selvan
and 22 other authors
Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer
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2021
Mojdeh Shakiba ,
Paul Zumbo ,
Gabriel Espinosa-Carrasco ,
Laura Menocal ,
Friederike Dündar ,
Sandra E. Carson ,
Emmanuel M. Bruno ,
Francisco J. Sanchez-Rivera ,
Scott W. Lowe ,
Steven Camara,
Richard P. Koche ,
Vincent P. Reuter ,
Nicholas D. Socci ,
Benjamin Whitlock ,
Fella Tamzalit
and 7 other authors
,
Paul Zumbo ,
Gabriel Espinosa-Carrasco ,
Laura Menocal ,
Friederike Dündar ,
Sandra E. Carson ,
Emmanuel M. Bruno ,
Francisco J. Sanchez-Rivera ,
Scott W. Lowe ,
Steven Camara,
Richard P. Koche ,
Vincent P. Reuter ,
Nicholas D. Socci ,
Benjamin Whitlock ,
Fella Tamzalit
and 7 other authors
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion
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Masato Ogishi ,
Rui Yang,
Caner Aytekin ,
David Langlais ,
Mathieu Bourgey ,
Taushif Khan,
Fatima Al Ali,
Mahbuba Rahman,
Ottavia M. Delmonte,
Maya Chrabieh,
Peng Zhang ,
Conor Gruber,
Simon J. Pelham ,
András N. Spaan ,
Jérémie Rosain
and 40 other authors
,
Rui Yang,
Caner Aytekin ,
David Langlais ,
Mathieu Bourgey ,
Taushif Khan,
Fatima Al Ali,
Mahbuba Rahman,
Ottavia M. Delmonte,
Maya Chrabieh,
Peng Zhang ,
Conor Gruber,
Simon J. Pelham ,
András N. Spaan ,
Jérémie Rosain
and 40 other authors
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
Download from www.nature.com
Kathryn C. Arbour ,
Hira Rizvi,
Andrew J. Plodkowski ,
Matthew D. Hellmann ,
Andrea Knezevic ,
Glenn Heller,
Helena A. Yu,
Marc Ladanyi,
Mark G. Kris,
Maria E. Arcila,
Charles M. Rudin ,
Piro Lito,
Gregory J. Riely
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,
Hira Rizvi,
Andrew J. Plodkowski ,
Matthew D. Hellmann ,
Andrea Knezevic ,
Glenn Heller,
Helena A. Yu,
Marc Ladanyi,
Mark G. Kris,
Maria E. Arcila,
Charles M. Rudin ,
Piro Lito,
Gregory J. Riely
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Matthew D. Hellmann ,
Nicoletta Bivi ,
Boris Calderon ,
Toshio Shimizu,
Brant Delafontaine,
Zhuqing Tina Liu,
Anna M. Szpurka ,
Victoria Copeland,
F. Stephen Hodi,
Sylvie Rottey,
Philippe Aftimos,
Yongzhe Piao,
Leena Gandhi,
Violeta Regnier Galvao,
Ching Leow
and 1 other authors
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,
Nicoletta Bivi ,
Boris Calderon ,
Toshio Shimizu,
Brant Delafontaine,
Zhuqing Tina Liu,
Anna M. Szpurka ,
Victoria Copeland,
F. Stephen Hodi,
Sylvie Rottey,
Philippe Aftimos,
Yongzhe Piao,
Leena Gandhi,
Violeta Regnier Galvao,
Ching Leow
and 1 other authors
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Kevin Litchfield,
James L. Reading ,
Clare Puttick,
Krupa Thakkar,
Chris Abbosh,
Robert Bentham ,
Thomas B. K. Watkins,
Rachel Rosenthal,
Dhruva Biswas ,
Andrew Rowan,
Emilia Lim,
Maise Al Bakir,
Virginia Turati,
José Afonso Guerra-Assunção,
Lucia Conde
and 13 other authors
,
Clare Puttick,
Krupa Thakkar,
Chris Abbosh,
Robert Bentham ,
Thomas B. K. Watkins,
Rachel Rosenthal,
Dhruva Biswas ,
Andrew Rowan,
Emilia Lim,
Maise Al Bakir,
Virginia Turati,
José Afonso Guerra-Assunção,
Lucia Conde
and 13 other authors
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
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2020
Daniel K. Wells ,
Marit M. van Buuren,
Kristen K. Dang ,
Vanessa M. Hubbard-Lucey,
Kathleen C. F. Sheehan ,
Katie M. Campbell ,
Andrew Lamb,
Jeffrey P. Ward ,
John Sidney,
Ana B. Blazquez,
Andrew J. Rech,
Jesse M. Zaretsky ,
Begonya Comin-Anduix,
Alphonsus H. C. Ng ,
William Chour
and 130 other authors
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,
Marit M. van Buuren,
Kristen K. Dang ,
Vanessa M. Hubbard-Lucey,
Kathleen C. F. Sheehan ,
Katie M. Campbell ,
Andrew Lamb,
Jeffrey P. Ward ,
John Sidney,
Ana B. Blazquez,
Andrew J. Rech,
Jesse M. Zaretsky ,
Begonya Comin-Anduix,
Alphonsus H. C. Ng ,
William Chour
and 130 other authors
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Patrick A. Ott ,
Siwen Hu-Lieskovan,
Bartosz Chmielowski ,
Ramaswamy Govindan,
Aung Naing,
Nina Bhardwaj ,
Kim Margolin,
Mark M. Awad ,
Matthew D. Hellmann ,
Jessica J. Lin ,
Terence Friedlander ,
Meghan E. Bushway,
Kristen N. Balogh,
Tracey E. Sciuto ,
Victoria Kohler
and 24 other authors
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,
Siwen Hu-Lieskovan,
Bartosz Chmielowski ,
Ramaswamy Govindan,
Aung Naing,
Nina Bhardwaj ,
Kim Margolin,
Mark M. Awad ,
Matthew D. Hellmann ,
Jessica J. Lin ,
Terence Friedlander ,
Meghan E. Bushway,
Kristen N. Balogh,
Tracey E. Sciuto ,
Victoria Kohler
and 24 other authors
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Kevin Litchfield ,
James L. Reading ,
Emilia L. Lim,
Hang Xu ,
Po Liu ,
Maise Al-Bakir,
Yien Ning Sophia Wong,
Andrew Rowan,
Samuel A. Funt ,
Taha Merghoub,
David Perkins,
Martin Lauss,
Inge Marie Svane,
Göran Jönsson,
Javier Herrero
and 5 other authors
,
James L. Reading ,
Emilia L. Lim,
Hang Xu ,
Po Liu ,
Maise Al-Bakir,
Yien Ning Sophia Wong,
Andrew Rowan,
Samuel A. Funt ,
Taha Merghoub,
David Perkins,
Martin Lauss,
Inge Marie Svane,
Göran Jönsson,
Javier Herrero
and 5 other authors
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
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Xuemei Ji ,
Semanti Mukherjee,
Maria Teresa Landi,
Yohan Bosse ,
Philippe Joubert,
Dakai Zhu,
Ivan Gorlov,
Xiangjun Xiao,
Younghun Han,
Olga Gorlova,
Rayjean J. Hung ,
Yonathan Brhane,
Robert Carreras-Torres,
David C. Christiani ,
Neil Caporaso
and 96 other authors
,
Semanti Mukherjee,
Maria Teresa Landi,
Yohan Bosse ,
Philippe Joubert,
Dakai Zhu,
Ivan Gorlov,
Xiangjun Xiao,
Younghun Han,
Olga Gorlova,
Rayjean J. Hung ,
Yonathan Brhane,
Robert Carreras-Torres,
David C. Christiani ,
Neil Caporaso
and 96 other authors
Protein-altering germline mutations implicate novel genes related to lung cancer development
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2019
Lawrence Fong,
Andrew Hotson,
John D. Powderly,
Mario Sznol,
Rebecca S. Heist,
Toni K. Choueiri,
Saby George ,
Brett G. M. Hughes,
Matthew D. Hellmann ,
Dale R. Shepard,
Brian I. Rini,
Shivaani Kummar,
Amy M. Weise,
Matthew J. Riese,
Ben Markman
and 18 other authors
,
Brett G. M. Hughes,
Matthew D. Hellmann ,
Dale R. Shepard,
Brian I. Rini,
Shivaani Kummar,
Amy M. Weise,
Matthew J. Riese,
Ben Markman
and 18 other authors
Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer
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Ila Datar,
Miguel F. Sanmamed,
Jun Wang,
Brian S. Henick,
Jungmin Choi,
Ti Badri,
Weilai Dong,
Nikita Mani,
Maria Toki,
Luis D. Mejías,
Maria D. Lozano,
Jose Luis Perez-Gracia,
Vamsidhar Velcheti,
Matthew D. Hellmann ,
Justin F. Gainor
and 10 other authors
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,
Justin F. Gainor
and 10 other authors
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Kyung Hae Jung,
Maria Ochoa de Olza,
Patricia LoRusso,
Howard Burris,
Michael Gordon,
Yung-Jue Bang,
Matthew D. Hellmann ,
Andrés Cervantes ,
Maria Ochoa de Olza,
Aurelien Marabelle,
F. Stephen Hodi,
Myung-Ju Ahn,
Leisha A. Emens,
Fabrice Barlesi,
Omid Hamid
and 13 other authors
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Andrés Cervantes ,
Maria Ochoa de Olza,
Aurelien Marabelle,
F. Stephen Hodi,
Myung-Ju Ahn,
Leisha A. Emens,
Fabrice Barlesi,
Omid Hamid
and 13 other authors
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Robert M. Samstein ,
Chung-Han Lee,
Alexander N. Shoushtari ,
Matthew D. Hellmann ,
Ronglai Shen,
Yelena Y. Janjigian,
David A. Barron,
Ahmet Zehir ,
Emmet J. Jordan,
Antonio Omuro,
Thomas J. Kaley,
Sviatoslav M. Kendall,
Robert J. Motzer ,
A. Ari Hakimi,
Martin H. Voss
and 42 other authors
,
Chung-Han Lee,
Alexander N. Shoushtari ,
Matthew D. Hellmann ,
Ronglai Shen,
Yelena Y. Janjigian,
David A. Barron,
Ahmet Zehir ,
Emmet J. Jordan,
Antonio Omuro,
Thomas J. Kaley,
Sviatoslav M. Kendall,
Robert J. Motzer ,
A. Ari Hakimi,
Martin H. Voss
and 42 other authors
Tumor mutational load predicts survival after immunotherapy across multiple cancer types
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Matthew D. Hellmann ,
Tudor-Eliade Ciuleanu,
Adam Pluzanski,
Jong Seok Lee,
Gregory A. Otterson,
Clarisse Audigier-Valette,
Elisa Minenza,
Helena Linardou,
Sjaak Burgers,
Pamela Salman,
Hossein Borghaei,
Suresh S. Ramalingam,
Julie Brahmer,
Martin Reck,
Kenneth J. O’Byrne
and 9 other authors
,
Tudor-Eliade Ciuleanu,
Adam Pluzanski,
Jong Seok Lee,
Gregory A. Otterson,
Clarisse Audigier-Valette,
Elisa Minenza,
Helena Linardou,
Sjaak Burgers,
Pamela Salman,
Hossein Borghaei,
Suresh S. Ramalingam,
Julie Brahmer,
Martin Reck,
Kenneth J. O’Byrne
and 9 other authors
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
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Matthew D. Hellmann ,
Tavi Nathanson,
Hira Rizvi,
Benjamin C. Creelan,
Francisco Sanchez-Vega ,
Arun Ahuja,
Ai Ni,
Jacki B. Novik,
Levi M. B. Mangarin,
Mohsen Abu-Akeel,
Cailian Liu,
Jennifer L. Sauter,
Natasha Rekhtman,
Eliza Chang,
Margaret K. Callahan
and 17 other authors
Download from discovery.ucl.ac.uk
,
Tavi Nathanson,
Hira Rizvi,
Benjamin C. Creelan,
Francisco Sanchez-Vega ,
Arun Ahuja,
Ai Ni,
Jacki B. Novik,
Levi M. B. Mangarin,
Mohsen Abu-Akeel,
Cailian Liu,
Jennifer L. Sauter,
Natasha Rekhtman,
Eliza Chang,
Margaret K. Callahan
and 17 other authors
Download from discovery.ucl.ac.uk
2017
Bertrand Routy ,
Emmanuelle Le Chatelier ,
Lisa Derosa,
Connie P. M. Duong ,
Maryam Tidjani Alou,
Romain Daillère ,
Aurélie Fluckiger ,
Meriem Messaoudene,
Conrad Rauber,
Maria P. Roberti,
Marine Fidelle,
Caroline Flament,
Vichnou Poirier-Colame,
Paule Opolon,
Christophe Klein
and 33 other authors
,
Emmanuelle Le Chatelier ,
Lisa Derosa,
Connie P. M. Duong ,
Maryam Tidjani Alou,
Romain Daillère ,
Aurélie Fluckiger ,
Meriem Messaoudene,
Conrad Rauber,
Maria P. Roberti,
Marine Fidelle,
Caroline Flament,
Vichnou Poirier-Colame,
Paule Opolon,
Christophe Klein
and 33 other authors
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
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