Ko Willems van Dijk
0000-0002-2172-7394
Leiden University Medical Center
134 papers found
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LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice
Apolipoprotein E2 (Lys146->Gln) Causes Hypertriglyceridemia due to an Apolipoprotein E Variant-Specific Inhibition of Lipolysis of Very Low Density Lipoproteins-Triglycerides
Very-low-density lipoprotein binding to the apolipoprotein E receptor 2 is enhanced by lipoprotein lipase, and does not require apolipoprotein E.
Use of transgenic mice to study the role of apolipoprotein E in lipid metabolism and atherosclerosis
Effect of Macrophage-Derived Mouse ApoE, Human ApoE3-Leiden, and Human ApoE2 (Arg158->Cys) on Cholesterol Levels and Atherosclerosis in ApoE-Deficient Mice
Transgenic mouse models to study the role of the macrophage scavenger receptor class A in atherosclerosis
Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages
Hyperlipidemia of ApoE2(Arg158-Cys) and ApoE3-Leiden Transgenic Mice Is Modulated Predominantly by LDL Receptor Expression
Apolipoprotein E Participates in the Regulation of Very Low Density Lipoprotein-Triglyceride Secretion by the Liver
Dissection of the complex role of apolipoprotein E in lipoprotein metabolism and atherosclerosis using mouse models
Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
Binding of -VLDL to Heparan Sulfate Proteoglycans Requires Lipoprotein Lipase, Whereas ApoE Only Modulates Binding Affinity
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE:
Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection
Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice
4.P.316 Generation of very low density lipoprotein receptor overexpressing mice
Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
141 Lipoprotein metabolism and atherosclerosis in APOE∗3Leiden mice
73 Effect of adenovirus mediated overexpression of human phospholipid transfer protein (PLTP) on the plasma lipoprotein profile in different strains of transgenic mice
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