American Society of Hematology, Blood Advances, 15(1), p. 1101-1106, 2017
DOI: 10.1182/bloodadvances.2017006411
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Key Points FAS-dependent apoptosis in Vδ1 T cells makes the latter possible culprits for the lymphadenopathy observed in patients with FAS mutations. Rapamycin and methylprednisolone resistance should prompt clinicians to look for Vδ1 T cell proliferation in ALPS-FAS patients.