The fruit of Persea schiedeana is consumed in various rural regions of Mexico and Central America and is mainly sold in local markets. Information regarding the ecological conditions where it grows and the potential for its distribution in Mexico has been little studied. The States of Chiapas, Hidalgo, Oaxaca, Puebla, Tabasco, and Veracruz in Mexico were explored to locate P. schiedeana trees. The ecological conditions of the places where P. schiedeana was found were characterized using thematic cartography and by evaluating the ecological niches to identify potential areas for its distribution. The trees were found in wide physiographic, geological, and edaphic conditions, but they were primarily located in semiwarm humid and warm humid climates. Persea schiedeana trees grow from almost sea level to 2000 m in altitude. Zones with the best developmental conditions for P. schiedeana were in the region of the high mountains in the center of Veracruz and the highland zone of northern Oaxaca. The oil obtained from the fruit of P. schiedeana trees growing at 1300 m had high oleic acid content. This wild fruit has the potential for obtaining new products for cosmetic and alimentary industries.