Published in
American Chemical Society, Journal of Medicinal Chemistry, 7(60), p. 2819-2839, 2017
DOI: 10.1021/acs.jmedchem.6b01665
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Discovery of 4-((3′R,4′S,5′R)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development
Journal article published in 2017 by
Angelo Aguilar,
Jianfeng Lu,
Liu Liu,
Ding Du 
,
Denzil Bernard,
Donna McEachern,
Sally Przybranowski,
Xiaoqin Li,
Ruijuan Luo,
Bo Wen,
Duxin Sun,
Hengbang Wang,
Jianfeng Wen,
Guangfeng Wang,
Yifan Zhai
and other authors.
,
Denzil Bernard,
Donna McEachern,
Sally Przybranowski,
Xiaoqin Li,
Ruijuan Luo,
Bo Wen,
Duxin Sun,
Hengbang Wang,
Jianfeng Wen,
Guangfeng Wang,
Yifan Zhai
and other authors.
This paper is made freely available by the publisher.
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