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American Society of Hematology, Blood, 2(126), p. 233-241, 2015

DOI: 10.1182/blood-2015-03-633537

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SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Journal article published in 2015 by Luca Malcovati, Mohsen Karimi, Elli Papaemmanuil, Ilaria Ambaglio, M. Jadersten, Martin Jädersten, Monika Jansson, Chiara Elena, Anna Gallì, Gunilla Walldin, Matteo G. Della Porta, Klas Raaschou-Jensen, Erica Travaglino, Klaus Kallenbach, Daniela Pietra and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points In MDS with ring sideroblasts, SF3B1 mutation defines a homogeneous subgroup with isolated erythroid dysplasia and favorable prognosis. MDS with ring sideroblasts and wild-type SF3B1 is mainly characterized by multilineage dysplasia and unfavorable prognosis.