Additional file 4: Figure S3. CRISPR/dCas9-mediated regulation of twelve native yeast promoters. Twelve yeast promoters as indicated were targeted with scRNAs in a total of 88 strains for regulation at various positions. Deviations from ’no gRNA’ control for each promoter is shown on second axis (relative MFI), and promoters with indicated distances from scRNA hybridization sites to TSS+1 are listed on first axis. Dark grey bars represent regulation with MCP-VPR (activation) and light grey bars regulation with PCP-Mxi1 (repression). GFP emission was measured following 24 hrs incubation and MFI calculated. MFI values are shown as mean ± s.d. from three (n = 3) biological replicate experiments (* = p