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Oxford University Press (OUP), The Journal of Clinical Endocrinology & Metabolism, 5(93), p. 1789-1795

DOI: 10.1210/jc.2007-2492

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Increased Plasma Osteoprotegerin Concentrations Are Associated with Indices of Bone Strength of the Hip

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Objective: Osteoprotegerin (OPG) is an important regulator of bone turnover through its effects on osteoclastogenesis, yet findings from previous studies of circulating OPG and commonly measured bone indices in humans have been conflicting. We conducted a cross-sectional study to evaluate the association between plasma OPG and femoral neck (FN) bone density (BMD) and geometry in a large cohort of women and men.