Dissemin is shutting down on January 1st, 2025

Published in

Wiley, European Journal of Immunology, 6(43), p. 1407-1412, 2013

DOI: 10.1002/eji.201243119

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The future of immunoimaging — Deeper, bigger, more precise, and definitively more colorful

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Data provided by SHERPA/RoMEO

Abstract

Immune cells are thoroughbreds, moving farther and faster and surveying more diverse tissue space than their non-hematopoietic brethren. Intravital 2-photon microscopy has provided insights into the movements and interactions of many immune cell types in diverse tissues, but much more information is needed to link such analyses of dynamic cell behavior to function. Here we describe additional methods whose application promises to extend our vision, allowing more complete, multiscale dissection of how immune cell positioning and movement are linked to system state, host defense, and disease.