Published in
Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 5(52), p. 2372
DOI: 10.1167/iovs.10-6268
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- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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LOXL1Promoter Haplotypes Are Associated with Exfoliation Syndrome in a U.S. Caucasian Population
Journal article published in 2011 by
Bao Jian Fan 
,
Louis R. Pasquale,
Douglas Rhee,
Tiansen Li,
Jonathan L. Haines,
Janey L. Wiggs
,
Louis R. Pasquale,
Douglas Rhee,
Tiansen Li,
Jonathan L. Haines,
Janey L. Wiggs
This paper is made freely available by the publisher.
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Abstract
In this study, LOXL1 promoter haplotypes were identified that are significantly associated with exfoliation syndrome in a U.S. Caucasian population. These results suggest that promoter region SNPs can influence LOXL1 gene expression, potentially causing a reduction of enzyme activity that may predispose to disease.