Oxford University Press, FEMS Microbiology Letters, 1(197), p. 11-18, 2001
DOI: 10.1111/j.1574-6968.2001.tb10575.x
Oxford University Press (OUP), FEMS Microbiology Letters, 1(197), p. 11-18
DOI: 10.1016/s0378-1097(01)00099-4
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How the immune system kills Mycobacterium tuberculosis is still a puzzle. The classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this.