Published in

The Korean Society of Cardiology, Korean Circulation Journal, 3(39), p. 87, 2009

DOI: 10.4070/kcj.2009.39.3.87

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Is Stem Cell-Based Therapy Going on or Out for Cardiac Disease?

Journal article published in 2009 by Ki Hyun Byun, Sung-Whan Kim
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Preprint: policy unknown
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Postprint: policy unknown
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Published version: policy unknown
Data provided by SHERPA/RoMEO

Abstract

Acute myocardial infarction and subsequent heart failure are leading causes of death worldwide. Stem cell-based therapies have improved cardiac function in recent clinical trials, but cardiomyocyte regeneration has not been demonstrated in human hearts. Angiogenesis and restoration of cardiac perfusion have been successfully performed using bone marrow derived stem cells and other adult stem cells. Resident cardiac stem cells are known to differentiate into multiple heart cell types, including cardiomyocytes. Furthermore, induced pluripotent stem cells are a focus of research due to the great potential for customized stem cell therapy.