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BMJ Publishing Group, BMJ Case Reports, nov30 1(2010), p. bcr0920103311-bcr0920103311

DOI: 10.1136/bcr.09.2010.3311

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Focal nodular hyperplasia with major sinusoidal dilatation: a misleading entity

Journal article published in 2010 by Hervé Laumonier, Nora Frulio, Christophe Laurent, Charles Balabaud, Jessica Zucman-Rossi ORCID, Paulette Bioulac-Sage
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Abstract

Focal nodular hyperplasia (FNH) is a benign liver lesion thought to be a non-specific response to locally increased blood flow. Although the diagnosis of FNH and hepatocellular adenoma (HCA) has made great progress over the last few years using modern imaging techniques, there are still in daily practice some difficulties concerning some atypical nodules. Here, the authors report the case of a 47-year-old woman with a single liver lesion thought to be, by imaging, an inflammatory HCA with major sinusoidal congestion. This nodule was revealed to be, at the microscopical level and after specific immunostaining and molecular analysis, an FNH with sinusoidal dilatation (so-called telangiectatic focal nodular hyperplasia).