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Elsevier, Journal of the American Academy of Child and Adolescent Psychiatry, 10(55), p. 896-905.e6

DOI: 10.1016/j.jaac.2016.05.025

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A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

Journal article published in 2016 by Christel M. (Christel) Middeldorp ORCID, Anke R. (Anke R.) Hammerschlag, Klaasjan G. (Klaasjan) Ouwens, Maria M. (Maria) M Groen-Blokhuis, M. M. Blokhuis, B. St Pourcain, B. (Beate) St Pourcain, Corina U. (Corina U.) Greven, Irene Pappa, M. (Magda) Pappa, Carla M. T. (Carla M. T.) Tiesler, Wei Q. (Wei) Ang, Ilja M. (Ilja) Nolte, N. (Natàlia) Vilor-Tejedor, J. (Jonas) Bacelis ORCID and other authors.
This paper is available in a repository.
This paper is available in a repository.

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Abstract

OBJECTIVE: The aims of this study were to elucidate the influence of common genetic variants on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify genetic variants that explain its high heritability, and to investigate the genetic overlap of ADHD symptom scores with ADHD diagnosis. METHOD: Within the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, genome-wide single nucleotide polymorphisms (SNPs) and ADHD symptom scores were available for 17,666 children (