We analyze the radial pressure profiles, the ICM clumping factor and the Sunyaev-Zel'dovich (SZ) scaling relations of a sample of simulated galaxy clusters and groups identified in a set of hydrodynamical simulations based on an updated version of the TreePM-SPH GADGET-3 code. Three different sets of simulations are performed: the first assumes non-radiative physics, the others include, among other processes, AGN and/or stellar feedback. Our results are analyzed as a function of redshift, ICM physics, cluster mass and cluster cool-coreness or dynamical state. In general, the mean pressure profiles obtained for our sample of groups and clusters show a good agreement with X-ray and SZ observations. Simulated cool-core (CC) and non-cool-core (NCC) clusters also show a good match with real data. We obtain in all cases a small (if any) redshift evolution of the pressure profiles of massive clusters, at least back to z=1. We find that the clumpiness of gas density and pressure increases with the distance from the cluster center and with the dynamical activity. The inclusion of AGN feedback in our simulations generates values for the gas clumping ($\sqrt C_{ρ}∼ 1.2$ at $R_{200}$) in good agreement with recent observational estimates. The simulated $Y_{SZ}-M$ scaling relations are in good accordance with several observed samples, especially for massive clusters. As for the scatter of these relations, we obtain a clear dependence on the cluster dynamical state, whereas this distinction is not so evident when looking at the subsamples of CC and NCC clusters. ; Comment: 22 pages, 14 figures, 2 tables. Submitted to MNRAS