Additional file 7: Figure S5. of Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome

Brasa, Sarah; Mueller, Arne; Jacquemont, SĂŠbastien; Hahne, Florian; Rozenberg, Izabela; Peters, Thomas; He, Yunsheng; McCormack, Christine; Gasparini, Fabrizio; Chibout, Salah-Dine; Grenet, Olivier; Moggs, Jonathan; Gomez-Mancilla, Baltazar; Terranova, RĂŠmi

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Additional file 7: Figure S5. of Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome

Published in 2016 by Sarah Brasa, Arne Mueller, SĂŠbastien Jacquemont, Florian Hahne, Izabela Rozenberg, Thomas Peters, Yunsheng He, Christine McCormack, Fabrizio Gasparini, Salah-Dine Chibout, Olivier Grenet, Jonathan Moggs, Baltazar Gomez-Mancilla, RĂŠmi Terranova

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Abstract

Linear regression analysis of the methylation (5mC) or hydroxymethylation (5hmC) assays and the different histones marks (H3K4me2, H3K9me2, H3K9me3, H4K20me1) in eight FXS patients PBMC samples. Graphs show the relationship with the highest coefficient of determination denoted RSq. The p value is indicated, and the dots gradient coloring represents the mRNA expression level for each sample, black for the highest expression level, and light grey for the lowest level. (PDF 547Â kb)