BETi upregulate MICA expression in different human MM cell lines. MICA, MICB, and PVR/CD155 cell surface expression were analyzed by immunofluorescence and flow cytometry on RPMI-8226, U266, ARP-1, and JJN3, respectively, after a 72 h treatment with JQ1. The MFI of MICA, MICB, and PVR/CD155 was calculated based on at least four independent experiments and evaluated by paired Student t test (*P