Protein-protein interaction network with the common SNP dataset. Notes: Proteins without connections were removed for clarity. Red circle, proteins related to hypoxia and the cardiovascular system from the GO categories; yellow circle, proteins related to the cardiovascular system from the literature; green dot, proteins related to hypoxia adaptation listed in a study by Zhang [9]. “line”: interaction with medium confidence; “bold line”: interaction with high confidence. (PDF 405 kb)