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Delays in postremission chemotherapy for Philadelphia chromosome negative acute lymphoblastic leukemia are associated with inferior outcomes in patients who undergo allogeneic transplant: An analysis from ECOG 2993/MRC UK ALLXII
Journal article published in 2016 by
Anita J. Kumar,
Phyllis A. Gimotty,
Joel Gelfand 
,
Georgina Buck,
Jacob M. Rowe,
Anthony H. Goldstone,
Adele Fielding,
David I. Marks,
Mark Litzow,
Elisabeth Paietta,
Hillard M. Lazarus,
Martin S. Tallman,
Selina M. Luger,
Alison W. Loren
,
Georgina Buck,
Jacob M. Rowe,
Anthony H. Goldstone,
Adele Fielding,
David I. Marks,
Mark Litzow,
Elisabeth Paietta,
Hillard M. Lazarus,
Martin S. Tallman,
Selina M. Luger,
Alison W. Loren
Abstract
Adults with acute lymphoblastic leukemia (ALL) have a poorer prognosis than children due to a high risk of relapse. One explanation may be variable adherence to dose-intense chemotherapy. However, little is known about risk factors for delays in therapy and their impact on survival.