Analysis with the exome array identifies multiple new independent variants in lipid loci

Kanoni, S.; Warren, Hr; Zhang, W.; Yaghootkar, H.; Waldenberger, M.; Zeggini, E.; Wareham, Nj; Masca, Ngd; Stirrups, Ke; Varga, Tv; Scott, Ra; Southam, L.; Müller-Nurasyid, M.; Couto Alves, A.; Strawbridge, Rj; Lataniotis, L.; Hashim, Nan; Besse, C.; Boland, A.; Braund, Ps; Connell, Jm; Dominiczak, A.; Farmaki, A.-E.; Franks, S.; Grallert, H.; Jansson, J.-H.; Karaleftheri, M.; Keinänen-Kiukaanniemi, S.; Matchan, A.; Pasko, D.; Peters, A.; Poulter, N.; Rayner, Nw; Renström, F.; Rolandsson, O.; Sabater-Lleal, M.; Sennblad, B.; Sever, P.; Shields, D.; Silveira, A.; Stanton, Av; Strauch, K.; Tomaszewski, M.; Tsafantakis, E.; Blakemore, Aif; Dedoussis, G.; Escher, Sa; Kooner, Js; McCarthy, Mi; Palmer, Cna; Hamsten, A.; Caulfield, Mj; Frayling, Tm; Tobin,; Jarvelin, M.-R.; Gieger, C.; Chambers, Jc; Munroe, Pb; Franks, Pw; Samani, Nj; Deloukas, P.

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Analysis with the exome array identifies multiple new independent variants in lipid loci

Journal article published in 2016 by S. Kanoni, Hr Warren, W. Zhang, H. Yaghootkar, M. Waldenberger, E. Zeggini, Nj Wareham, Ngd Masca, Ke Stirrups, Tv Varga

, Ra Scott, L. Southam, M. Müller-Nurasyid, A. Couto Alves, Rj Strawbridge and other authors.

This paper is available in a repository.

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Abstract

It has been hypothesized that low frequency (1–5% minor allele frequency (MAF)) and rare (1000-fold more significant than the previous sentinel variant and not in close LD (six had MAF

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Analysis with the exome array identifies multiple new independent variants in lipid loci

Abstract