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Mary Ann Liebert, Thyroid, 6(24), p. 958-965

DOI: 10.1089/thy.2013.0573

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Hobnail Variant of Papillary Thyroid Carcinoma: An Institutional Case Series and Molecular Profile

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Background: Papillary thyroid carcinoma (PTC) is increasing in incidence while mortality is unchanged. Identifying patients with higher risk of recurrence and death is essential. Case series identify the hobnail variant of PTC (HVPTC), which is characterized by micropapillary architecture, apocrine features, and loss of cellular polarity. Herein, we describe the clinical course, pathologic features, and mutational profile of patients at our institution with HVPTC.