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Genome-wide association analyses in 128,266 individuals identifies new morningness and sleep duration loci
Journal article published in 2016 by
Samuel E. (Samuel E.) Jones 
,
Jessica Tyrrell,
A. W. R. Tyrrell,
Andrew R. (Andrew) Wood ,
Robin N. (Robin N.) Beaumont ,
Katherine S. (Katherine S.) Ruth ,
Marcus A. (Marcus A.) Tuke,
Hanieh Yaghootkar,
Youna Hu,
Maris Teder-Laving,
Caroline Hayward,
Till Roenneberg,
James F. (James F.) Wilson ,
Fabiola M. (Fabiola) Del Greco,
Andrew Aa Hicks
and other authors.
,
Jessica Tyrrell,
A. W. R. Tyrrell,
Andrew R. (Andrew) Wood ,
Robin N. (Robin N.) Beaumont ,
Katherine S. (Katherine S.) Ruth ,
Marcus A. (Marcus A.) Tuke,
Hanieh Yaghootkar,
Youna Hu,
Maris Teder-Laving,
Caroline Hayward,
Till Roenneberg,
James F. (James F.) Wilson ,
Fabiola M. (Fabiola) Del Greco,
Andrew Aa Hicks
and other authors.
Abstract
Disrupted circadian rhythms and reduced sleep duration are associated with several human diseases, particularly obesity and type 2 diabetes, but until recently, little was known about the genetic factors influencing these heritable traits. We performed genome-wide association studies of self-reported chronotype (morning/evening person) and self-reported sleep duration in 128,266 white British individuals from the UK Biobank study. Sixteen variants were associated with chronotype (P