Published in
Royal Society of Chemistry, Chemical Communications, 27(52), p. 4922-4925, 2016
DOI: 10.1039/c6cc00831c
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Synthesis of 2-fluoro-2-pyrrolines via tandem reaction of -trifluoromethyl-, -unsaturated carbonyl compounds with N-tosylated 2-aminomalonates
Journal article published in 2016 by
Jieru Yang,
Xiaofan Zhou,
Yuanjing Xiao,
Junliang Zhang,
Yu Zeng,
Chaoqian Huang
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Abstract
A simple base-mediated synthesis of synthetically valuable 2-fluoro-2-pyrrolines from α-trifluoromethyl-α,β-unsaturated carbonyl compounds and N-tosylated 2-aminomalonates was developed.