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Public Library of Science, PLoS ONE, 1(7), p. e29829, 2012

DOI: 10.1371/journal.pone.0029829

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Pathological and Incidental Findings on Brain MRI in a Single-Center Study of 229 Consecutive Girls with Early or Precocious Puberty

Journal article published in 2012 by Signe Sloth Mogensen, Lise Aksglaede, Annette Mouritsen, Kaspar Sørensen, Katharina M. Main, Peter Gideon, Anders Juul ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Central precocious puberty may result from organic brain lesions, but is most frequently of idiopathic origin. Clinical or biochemical factors which could predict a pathological brain MRI in girls with CPP have been searched for. With the recent decline in age at pubertal onset among US and European girls, it has been suggested that only girls with CPP below 6 years of age should have brain MRI performed.