This study examined the psychometric properties of the Satisfaction with Life Scale (SWLS) in terms of internal consistency reliability, factorial validity, and measurement invariance across gender, age, residential region (metropolitan area/county town/rural area), educational level, and household income with a nationally representative sample of 4,795 participants in China. The percentages of male (47.0%) and female (53.0%) participants were about equal, and the mean age was 38.56 years (SD = 11.87). The results show that the SWLS has a high internal consistency reliability, a one-factor structure (with a wording effect on Items 4 and 5), strict invariance across gender, partial strict invariance across education (Items 1, 2 and 3), and partial strong invariance across age, income (Items 1, 2 and 3) and residential region (Items 1 and 2). The non-invariance of some items across age and region is discussed in terms of the rapid economic and social transitions of China in the past three decades.