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Elsevier, Archives of Cardiovascular Diseases Supplements, 1(15), p. 152-153, 2023

DOI: 10.1016/j.acvdsp.2022.10.293

Wiley, European Journal of Heart Failure, 7(15), p. 717-723

DOI: 10.1093/eurjhf/hft028

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Heart failure in elderly patients: distinctive features and unresolved issues

Journal article published in 2013 by M. T. Bailly, Valentina Lazzarini, Robert J. Mentz, X. Leahova Cerchez, Marco Metra ORCID, Christopher M. O'Connor, F. Bailly, E. Berthelot, Mona Fiuzat, N. Hrynchyshyn, T. Goncalves, P. Jourdain
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The prevalence of heart failure (HF) increases with age. While clinical trials suggest that contemporary evidence-based HF therapies have reduced morbidity and mortality, these trials largely excluded the elderly. Questions remain regarding the clinical characteristics of elderly HF patients and the impact of contemporary therapies on their outcomes. This review presents the epidemiology of HF in the elderly and summarizes the data on the pathophysiology of the ageing heart. The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted.