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American Society of Hematology, Blood, 13(127), p. e12-e23, 2016

DOI: 10.1182/blood-2015-10-677393

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Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model

Journal article published in 2016 by Nicola K. Wilson, Stefan Schoenfelder, Rebecca Hannah, M. Sanchez Castillo, Manuel Sánchez Castillo, Judith Schutte, Vasileios Ladopoulos, Joanna Mitchelmore, Debbie K. Goode, Fernando J. Calero-Nieto, Victoria Moignard, Adam C. Wilkinson, Isabel Jimenez-Madrid, Sarah Kinston, Mikhail Spivakov ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points New genome-wide maps for 17 TFs, 3 histone modifications, DNase I sites, Hi-C, and Promoter Capture Hi-C in a stem/progenitor model. Integrated analysis shows that chromatin loops in a stem/progenitor model are characterized by specific TF occupancy patterns.