Published in

American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 12(59), p. 7906-7910, 2015

DOI: 10.1128/aac.00568-15

Links

Tools

Export citation

Search in Google Scholar

Methicillin-Resistant Staphylococcus aureus Grown on Vancomycin-Supplemented Screening Agar Displays Enhanced Biofilm Formation

Journal article published in 2015 by Wenjiao Chang, Ding Ding, Shanshan Zhang, Yuanyuan Dai, Qing Pan, Huaiwei Lu, Qingli Luo, Jilong Shen, Xiaoling Ma
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

ABSTRACT Brain heart infusion agar containing 3 mg/liter vancomycin (BHI-V3) was used to screen for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA). There was markedly greater biofilm formation by isolates that grew on BHI-V3 than by strains that did not grow on BHI-V3. Increased biofilm formation by hVISA may be mediated by FnbA- and polysaccharide intercellular adhesin-dependent pathways, and upregulation of atlA and sarA may also contribute to enhanced biofilm formation by hVISA upon prolonged exposure to vancomycin.