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BMJ Publishing Group, Thorax, 1(60), p. 60-62, 2005

DOI: 10.1136/thx.2004.029678

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Transbronchial biopsies provide longitudinal evidence for epithelial chimerism in children following sex mismatched lung transplantation

Journal article published in 2005 by D. Rampling, P. Aurora, D. Bonnet, H. Spencer, S. L. Hart ORCID, A. Jaffe
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Background: Recent reports have shown evidence of host derived parenchymal engraftment in several human allografts including the lung, leading to speculation that stem cell therapy may be useful for lung repair in diseases such as cystic fibrosis (CF). To date, previous studies have looked at single surgical or autopsy specimens and no longitudinal studies have been reported. The aim of this study was to assess whether transbronchial biopsies could be used to study the time course of chimerism following lung transplantation.