Published in

American Society for Microbiology, Journal of Bacteriology, 2(190), p. 759-763, 2008

DOI: 10.1128/jb.01151-07

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LmrR Is a Transcriptional Repressor of Expression of the Multidrug ABC Transporter LmrCD in Lactococcus lactis

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT LmrCD is an ABC-type multidrug transporter in Lactococcus lactis . LmrR encodes a putative transcriptional regulator. In a Δ lmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD and interacts with drugs that cause lmrCD up-regulation. This suggests that LmrR is a drug-dependent transcriptional regulator of lmrCD expression.