American Society for Microbiology, Journal of Bacteriology, 2(190), p. 759-763, 2008
DOI: 10.1128/jb.01151-07
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ABSTRACT LmrCD is an ABC-type multidrug transporter in Lactococcus lactis . LmrR encodes a putative transcriptional regulator. In a Δ lmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD and interacts with drugs that cause lmrCD up-regulation. This suggests that LmrR is a drug-dependent transcriptional regulator of lmrCD expression.