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Royal Society of Chemistry, RSC Advances, 29(5), p. 22431-22448

DOI: 10.1039/c5ra01170a

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Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We here describe the development of potent inhibitors of the malaria parasite enzyme subtilisin-like protease 1 (PfSUB1).