Baiyangdian lake is typical macrophytic lake, located in North China. With the economic and social development, as well as the impact of global climate change, the water pollution problem has been being a serious impact on the salubrious development of regional ecosystems. The local government has adopted a change of water storage basin to approach to fundamentally solve the problems of water pollution with the ecological water transfer in lake basins. In this paper, collecting the typical water pollutants data before and after ecological water transfer, using of ArcGIS software we have researched the diffusion mode and the enrichment regulation of the water pollutants from the perspective of spatial distribution caused by the ecological water transfer. The results show that there has a strong detention of the pollutants spread in Baiyangdian lake. With the ecological water transfer, there is a positive significance onto the local water deterioration, but not a fundamental solution onto the whole lake environmental issues. It still needs to develop the integrated control-rehabilitation managements and technologies for water pollutants combined with special land-water broken terrain and the local climate in Baiyangdian lake.