The research on drillstring dynamics is necessary for improving drilling efficiency and safety. In this investigation, a multibody dynamical model for 3D full hole drillstring system is presented based on the Absolute Nodal Coordinate Formulation (ANCF). The drillstring is modeled with the ANCF beam element. The absolute nodal coordinate formulation of the beam element as well as the boundary conditions at the top-drive and drill-bit, and the contact/friction model between drillstring and wellbore are also investigated. The dynamic governing equation for full hole drillstring system is given and solved by the backward differentiation formulation (BDF) for differential algebraic equations (DAEs). The developed multibody dynamic solver is capable of analyzing full coupled vibration for the full hole drillstring system. It can play a certain role in drillstring dynamics researches and engineering applications.