Cochrane Collaboration, Cochrane Database of Systematic Reviews
DOI: 10.1002/14651858.cd001319
Cochrane Collaboration, Cochrane Database of Systematic Reviews
DOI: 10.1002/14651858.cd001319.pub2
Cochrane Collaboration, Cochrane Database of Systematic Reviews
DOI: 10.1002/14651858.cd001319.pub3
Full text: Download
No strong evidence to be certain of the safety of any particular type of colloid solution for replacing blood fluids When a person is bleeding heavily, the loss of fluid volume in their veins can lead to shock, so they need fluid resuscitation. Colloids and crystalloids are two types of solutions used to replace lost blood fluid (plasma). They include blood and synthetic products. Both types appear to be similarly effective at resuscitation, but one type of colloid (human albumin) was found by another Cochrane review to increase deaths. Different colloids may have different effects. However, the review of trials found there is not enough evidence to be sure that any particular colloid is safer than any other