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Canadian Science Publishing, Canadian Journal of Chemistry, 8(93), p. 858-863, 2015

DOI: 10.1139/cjc-2014-0579

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Resolution of malic acid by (+)-cinchonine and (–)-cinchonidine

Journal article published in 2015 by Nikoletta B. Báthori, Ayesha Jacobs, Mawonga Mei, Luigi R. Nassimbeni ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

(+)-Cinchonine and (–)-cinchonidine have been employed to resolve rac-malic acid. The resulting salts contain the D-malate anion in both cases. The cinchoninium and cinchonidinium L-malates were also crystallised, and the structures of all four salts were analysed in terms of their nonbonding interactions. All four structures display extensive hydrogen bonding, and it is shown that the D-malate salts are more efficiently packed.