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Nature Research, Nature Genetics, 7(44), p. 777-782, 2012

DOI: 10.1038/ng.2307

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Genome-wide association analysis identifies susceptibility loci for migraine without aura.

Journal article published in 2012 by Arn M. J. M. van den Maagdenberg, Tobias Freilinger, Cornelia M. van Duijn, B. De Vries, Verneri Anttila ORCID, Boukje de Vries, Rainer Malik, W. P. J. Van Oosterhout, Ville Artto, Unda Todt, Mikko Kallela, Eija Hamalainen, Eija Hämäläinen, Jessica Fernandez-Morales, Gisela M. Terwindt and other authors.
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic symptoms. To identify common genetic variants associated with this migraine type, we analyzed genome-wide association data of 2,326 clinic-based German and Dutch individuals with migraine without aura and 4,580 population-matched controls. We selected SNPs from 12 loci with 2 or more SNPs associated with P values of