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American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 6(182), p. 745-751, 2010

DOI: 10.1164/rccm.201003-0326oc

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Survival in Critical Illness Is Associated with Early Activation of Mitochondrial Biogenesis

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Rationale: We previously reported outcome-associated decreases in muscle energetic status and mitochondrial dysfunction in septic patients with multiorgan failure. We postulate that survivors have a greater ability to maintain or recover normal mitochondrial functionality.