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Oxford University Press (OUP), Bioinformatics, 4(26), p. 580-581

DOI: 10.1093/bioinformatics/btp710

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GWAF: an R package for genome-wide association analyses with family data

Journal article published in 2009 by Ming-Huei Chen, Qiong Yang ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Summary: GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.