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Royal Society of Chemistry, RSC Advances, 60(5), p. 48551-48557, 2015

DOI: 10.1039/c5ra04804d

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Identification of the first surrogate agonists for the G protein-coupled receptor GPR132

Journal article published in 2015 by Mohamed A. Shehata, Hanna Belcik Christensen, Hanna Belcik Christensen, Vignir Isberg, Daniel Sejer Pedersen ORCID, Andreas Bender, Hans Bräuner-Osborne ORCID, David E. Gloriam
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We report the first pharmacological tool agonist for in vitro characterization of the orphan receptor GPR132, preliminary structure–activity relationships based on 32 analogs and a suggested binding mode from docking.