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Oxford University Press (OUP), Bioinformatics, 10(30), p. 1363-1369

DOI: 10.1093/bioinformatics/btu049

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Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

Journal article published in 2014 by Martin J. Aryee, Andrew E. Jaffe, Hector Corrada-Bravo, Christine Ladd-Acosta, Andrew P. Feinberg, Kasper D. Hansen ORCID, Rafael A. Irizarry
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Motivation: The recently released Infinium HumanMethylation450 array (the ‘450k’ array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features. Although less comprehensive than high-throughput sequencing-based techniques, this product is more cost-effective and promises to be the most widely used DNAm high-throughput measurement technology over the next several years.