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Bentham Science Publishers, Current Topics in Medicinal Chemistry, 18(6), p. 1927-1970

DOI: 10.2174/156802606778522168

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Selective Agents for Serotonin2C (5-HT2C) Receptor

Journal article published in 2006 by Enza Lacivita ORCID, Marcello Leopoldo
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The serotonin2C (5-HT2C) receptor has attracted a lot of attention owing to its role in appetite regulation, depression, obsessive-compulsive disorder (OCD), panic disorders, and substance abuse. This review summarizes nonpatent and patent literature up to November 2005 that deals with the synthesis and characterization of selective 5-HT2C receptor agonists and antagonists. Highlights on structure-activity relationships have been included, when possible.