Published in
American Society of Hematology, Blood, 7(127), p. 898-907, 2016
DOI: 10.1182/blood-2015-08-664995
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- American Society of Hematology | PDF
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- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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ICAM-1 expressing neutrophils exhibit enhanced effector functions in murine models of endotoxemia
Journal article published in 2015 by
Abigail Woodfin,
Martina Beyrau,
Mathieu-Benoit Voisin,
Bin Ma,
James R. Whiteford,
Peter L. Hordijk 
,
Nancy Hogg,
Sussan Nourshargh
,
Nancy Hogg,
Sussan Nourshargh
This paper is made freely available by the publisher.
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Abstract
Key PointsMurine neutrophils can be stimulated by LPS to express de novo ICAM-1 in vitro and in murine models of endotoxemia in vivo. Neutrophil ICAM-1 expression correlated with enhanced phagocytosis and ROS generation, and ICAM-1 deficiency caused defective phagocytosis.