Defining the role of common variation in the genomic and biological architecture of adult human height.

Ärnl, Johan; de Andrade, Mariza M.; de Boer, Rudolf A. Ra; van der Klauw, Melanie M. Mm; den Ruijter Hester, M.; Zonzin, Pietro P.; Ziegler, Andreas A.; de Bakker Paul, I. W.; Ziegler, Andreas A; Zheng, Wei W.; van Duijn Cornelia, M.; Zhang, Weihua W.; Yee, Jean J.; Yee, Jean J; Young, Alicia A.; Wood, Andrew R. Ar; Zhao, Jing Hua JH; Wang, Zhaoming Z; Yang, Jian J.; Wang, Zhaoming Z.; Schumacher, Fredrick R.; Schumacher, Fredrick R. Fr; Wilkens, Lynne R.; Wang, Zhaoming; Wilkens, Lynne R. Lr; Randall, Joshua C. Jc; Scherag, André Andre; Ritchie, Marylyn M.; Vinkhuyzen, Anna Ae E. Aa; Vedantam, Sailaja S.; Westra, Harm-Jan Hj; Starren, Justin J.; Winkler, Thomas W. Tw; Workalemahu, Tsegaselassie T.; Wang, Z.; Rasmussen, Luke L.; Waudby, Carol C.; Reeser, Jonathan J.; Wilke, Russell A. Ra; Smith, Maureen E. Me; Wolf, Wendy A. Wa; Thompson, William K. Wk; van der Laan, Sander W. Sw; van Setten, Jessica J.; Wang, Zm; Savova, Guergana G.; Yengo, Loïc Loïc; Wu, Joel J.; Zhang, Weihua; Wolfgang, Hoffmannm; Ärnlöv, Johan; Spangler, Leslie L.; Trinidad, Susan Brown SB; Roden, Dan M. Dm; Warwick Daw, E.; Schildcrout, Jonathan S. Js; Xu, Hua H.; Ramirez, Andrea Havens AH; Pulley, Jill J.; Rosmalen, Judith G. M. Jg; Slaets, Joris P. Jp; Wolffenbuttel, Bruce H. R. Bh; Wijmenga, Cisca C.; Voight, Benjamin F. Bf; Purcell, Shaun S.; Ritchie, Marylyn M; Prokopenko, Inga I.; Reilly, Muredach P.; de Groot, Lisette C. P. G. M. Lc; Ried, Janina S. Js; Rader, Daniel J. Dj; Van Vliet-Ostaptchouk, Jana V. Jv; Ripke, Stephan S.; Spertus, John A. Ja; Shungin, Dmitry D.; Stoll, Monika M.; Stancáková, Alena A.; Strawbridge, Rona J. Rj; Siscovick, David S. Ds; Sung, Yun Ju YJ; Tanaka, Toshiko T.; Shin, Jianxin; Teumer, Alexander A.; Trompet, Stella S.; Schwartz, Stephen M. Sm; Tubaro, Marco M.; Ribichini, Flavio F.; Rossi, Marco M.; Van Der Laan, Sander W.; Van Vliet-Ostaptchouk, Jv; Subirana, Isaac I.; Ramos, Rafael R.; Sala, Joan J.; Williams, Gordon G.; Voight, Benjamin F. B.; Schunkert, I. Heribert I; Spreafico, Marta M.; Surti, Aarti A.; Thompson, John R.; Schwartz, Stephen M Sm; Siscovick, David S Ds; Schumacher, Fredrick Fr; Wright, Benjamin J. Bj; Stark, Klaus K.; Schreiber, Stefan S.; Purcell, Shaun S; Voight, Benjamin F Bf; Wilkens, Lynne Lr; Scholz, Michael M.; Subirana, Isaac I; Wilensky, Robert R.; Setten, J. van; Qasim, Atif A.; Vliet-Ostaptchouk, J. V. Van; Waksman, Ron R.; Satler, Lowell L.; Walker, Max C. Mc; Waterworth, Dawn M. Dm; Scheffold, Thomas T.; The, MIGen Consortium; van Dijk, Suzanne S.; The, Page Consortium; van Schoor, Natasja M. Nm; Xie, Changchun C.; van der Velde, Nathalie; van Heemst, Diana D.; Tönjes, Anke; van Oort, Floor Va A. Fv; Toenjes, Anke; Siscovick, David D.; Rader, Daniel J Dj; Williams, Rasheeda R.; Wouter Jukema, J.; Spertus, John A Ja; Stark, Klaus K; Zhang, Qunyuan Qy; Taylor, Kira K.; Th, Pers; Schreiber, Stefan S; Quibrera, Miguel M.; de Faire, Ulf U.; Volzke, Henry; den Ruijter, Hester M. Hm; Voelzke, Henry; Thornton-Wells, Tricia T.; Restrepo, Nicole N.; Umans, Jason J.; Wilson, Sarah S.; Spencer, Kylee K.; Wang, Hansong H.; Shohet, Ralph R.; Stram, Daniel D.; Tiirikainen, Maarit M.; Wu, Chunyuan C.; Rosse, Stephanie S.; Study, LifeLines Cohort; Rayner, Nigel W. Nw; Renstrom, Frida F.; Robertson, Neil R. Nr; Rose, Lynda M. Lm; Roussel, Ronan R.; Schumacher, Fr R.; Sanna, Serena S.; Scharnagl, Hubert H.; Scholtens, Salome S.; de Bakker, Paul Iw W. Pi; Schunkert, Heribert H.; Scott, Robert A. Ra; Sehmi, Joban J.; Seufferlein, Thomas T.; Shi, Jianxin J.; Silventoinen, Karri K.; Smit, Johannes H. Jh; Smith, Albert Vernon AV; Smolonska, Joanna J.; Stanton, Alice V. Av; Stirrups, Kathleen K.; Stott, David J. Dj; Stringham, Heather M. Hm; Sundström, Johan J.; Swertz, Morris A.; Syvänen, Ann-Christine Ac; Tayo, Bamidele O. Bo; Van Dijk, Suzanne; Thorleifsson, Gudmar G.; Van Schoor, Natasja M.; Tyrer, Jonathan P. Jp; Van Der Velde, N.; Van Heemst, Diana; Van Oort, Floor V. A.; van der Harst, Pim P.; Vermeulen, Sita H. Sh; Verweij, Niek N.; Vonk, Judith M. Jm; Zanen, Pieter P.; Waite, Lindsay L. Ll; Waldenberger, Melanie M.; Wilkens, Lr R.; Wennauer, Roman R.; Willenborg, Christina C.; Wilsgaard, Tom T.; Wojczynski, Mary K. Mk; Wong, Andrew A.; Wright, Alan F. Af; van Duijn, Cornelia M. Cm; Price, Jackie F. Jf; Qi, Lu L.; Raitakari, Olli T. Ot; Rankinen, Tuomo T.; Rao, Dc C. Dc; Rice, Treva K. Tk; Ritchie, Marylyn D.; Rudan, Igor I.; Salomaa, Veikko; Samani, Nilesh J. Nj; Saramies, Jouko J.; Sarzynski, Mark A.; Schwarz, Peter Eh H. Pe; Sebert, Sylvain S.; Sever, Peter P.; Shuldiner, Alan R. Ar; Sinisalo, Juha J.; Steinthorsdottir, Valgerdur; Stolk, Ronald P. Rp; Tardif, Jean-Claude Jc; Tönjes, Anke A.; Tremblay, Angelo A.; Tremoli, Elena E.; Virtamo, Jarmo J.; Vohl, Marie-Claude Mc; Tm, Frayling; Pérusse, Louis L.; Quertermous, Thomas T.; Rauramaa, Rainer R.; Reinmaa, Eva E.; Ridker, Paul M. Pm; Rivadeneira, Fernando F.; Rotter, Jerome I. Ji; Saaristo, Timo E. Te; Saleheen, Danish D.; Schlessinger, David D.; Slagboom, Pe Eline PE; Snieder, Harold H.; Van Der Harst, Pim; Spector, Tim D. Td; Strauch, Konstantin K.; Stumvoll, Michael M.; Tuomilehto, Jaakko J.; Uusitupa, Matti M.; Völzke, Henry H.; Walker, Mark M.; Wareham, Nicholas J. Nj; Watkins, Hugh H.; Wichmann, He-Erich He; Wilson, James F. Jf; Speliotes, Elizabeth K. Ek; Thorsteinsdottir, Unnur U.; Strachan, David P. Dp; Van Duijn, Cm M.; Stefansson, Kari K.; Uitterlinden, André G. Ag; Willer, Cristen J. Cj; Weedon, Michael N. Mn; Visscher, Peter M. Pm; Pers, Tune H. Th; Chu, Audrey Y. Ay; Buchkovich, Martin L. Ml; Esko, Tonu Tõnu; Croteau-Chonka, Damien C. Dc; Day, Felix R. Fr; Jackson, Anne U. Au; Lo, Ken Sin KS; Locke, Adam E. Ae; Mägi, Reedik R.; Porcu, Eleonora Evelin; Mihailov, Evelin E.; Peissig, Peggy P.; Absher, Devin D.; Albrecht, Eva E.; Anderson, Denise D.; Baron, Jeffrey J.; Beekman, Marian M.; Demirkan, Ayse Ayşe; Ehret, Georg Benedikt Gb; Gustafsson, Stefan S.; Feenstra, Bjarke B.; Feitosa, Mary F.; Fischer, Krista K.; Fraser, Ross M. Rm; Goel, Anuj A.; Gong, Jian J.; Kanoni, Stavroula S.; Kleber, Marcus E. Me; Kristiansson, Kati K.; Ar, Wood; Lim, Unhee U.; A. E., Justice; Lotay, Vaneet; Lui, Julian C. Jc; Mangino, Massimo M.; Postma, Dirkje S. Ds; Estrada, Karol K.; Medina-Gomez, Carolina C.; Nalls, Michael A.; Nyholt, Dale R. Dr; Leach, Im M.; Palmer, Cameron D. Cd; Luan, Jian'An Jian’an; Pasko, Dorota D.; Pechlivanis, Sonali S.; Kutalik, Zoltán Zoltán; Peltonen, Leena L.; Peyvandi, Flora F.; Amin, Najaf N.; Justice, Anne E.; Afzal, Uzma U.; Piazza, Alberto A.; Arscott, Gillian M. Gm; Bandinelli, Stefania S.; Barrett, Amy A.; Bellis, Claire C.; Bennett, Amanda J. Aj; Berne, Christian C.; Blüher, Matthias M.; Bolton, Jennifer L. Jl; Böttcher, Yvonne Y.; Boyd, Heather A. Ha; Bruinenberg, Marcel M.; Peltonen, Leena L; Buckley, Brendan M. Bm; Preuss, Michael M.; Buyske, Steve Steven; Caspersen, Ida H. Ih; Chines, Peter S. Ps; Duan, Yanan Y.; Clarke, Robert R.; Claudi-Boehm, Simone S.; Cooper, Matthew M.; Daw, Ew Warwick EW; De Jong, Pim A. Pa; Deelen, Joris J.; Fall, Tove T.; Delgado, Graciela G.; Denny, Josh C. Jc; Pichard, Augusto D. Ad; Dhonukshe-Rutten, Rosalie R.; Dimitriou, Maria M.; Doney, Alex Sf F. As; Dörr, Marcus M.; Fehrmann, Rudolf R.; Eklund, Niina N.; Eury, Elodie E.; Folkersen, Lasse L.; Garcia, Melissa E. Me; Geller, Frank F.; Giedraitis, Vilmantas; Go, Alan S. As; Ferreira, Teresa T.; Grallert, Harald H.; Grammer, Tanja B. Tb; Gräßler, Jürgen J.; Grönberg, Henrik H.; Groves, Christopher J. Cj; Haessler, Jeff Jeffrey; Hall, Per; De Groot, Lisette C. P. G. M.; Haller, Toomas T.; Preuss, Michael M; Hallmans, Goran Göran; Hannemann, Anke A.; Karjalainen, Juha J.; Hartman, Catharina A. Ca; Hassinen, Maija M.; Perusse, Louis; Hayward, Caroline C.; Pérusse, Louis; Heard-Costa, Nancy L. Nl; Helmer, Quinta Q.; Person, Sharina S.; Hemani, Gibran G.; Henders, Anjali K. Ak; Hillege, Hans L. Hl; Hlatky, Mark A.; Hoffmann, Wolfgang W.; Hoffmann, Per P.; Holmen, Oddgeir O.; Houwing-Duistermaat, Jeanine J. Jj; Pendergrass, Sarah S.; Illig, Thomas T.; Isaacs, Aaron A.; James, Alan L. Al; Jeff, Janina Jarina; Johansen, Berit Bent; Jolley, Jennifer J.; Johansson, Å.; Juliusdottir, Thorhildur T.; Junttila, Juhani J.; Prentice, Ross R.; Kho, Abel N.; Kinnunen, Leena L.; Klopp, Norman N.; Kocher, Thomas T.; Chun, Audrey Y.; Kratzer, Wolfgang W.; Ae, Anne E.; Lichtner, Peter P.; Johansson, Åsa Å; Lind, Lars L.; Buyske, Steven S.; Lindström, Jaana J.; Mägi, Reedik; Lobbens, Stéphane Stéphane; Haessler, Jeffrey J.; Lorentzon, Mattias Matthias; Hall, Per P.; Lu, Yingchang Yc; Lyssenko, Valeriya; Kho, Abel N. An; Magnusson, Patrik Ke E. Pk; Maegi, Reedik; Mahajan, Anubha A.; Ae, Justice; Maillard, Marc M.; Magi, Reedik; McArdle, Wendy L. Wl; Pagege, Consortium; McKenzie, Colin A. Ca; Ju Sung, Yun; McLachlan, Stela S.; McLaren, Paul J. Pj; McCarty, Catherine A. Ca; Menni, Cristina C.; Johansson, Åsa; Berg, Richard R.; Merger, Sigrun S.; Milani, Lili L.; Moayyeri, Alireza A.; Linneman, James J.; Monda, Keri L. Kl; Böttcher, Yvonne; Morken, Mario A.; Miller, Aaron A.; Müller, Gabriele G.; Müller-Nurasyid, Martina M.; E., Anne; Musk, Arthur W. Aw; Choudary, Vidhu; Narisu, Narisu N.; Nauck, Matthias M.; Nolte, Ilja M. Im; Chen, Lin L.; Nöthen, Markus M. Mm; Pilz, Stefan S.; Oozageer, Laticia L.; Kitchner, Terrie T.; Mateo Leach, Irene I.; Fost, Norman N.; Chisholm, Rex L. Rl; Avila, Pedro C. Pc; Greenland, Philip P.; Ay, Chu; Arnl, Johan J.; Kibbe, Warren A. Wa; Lemke, Amy A. Aa; Lowe, William L. Wl; Pacheco, Jennifer A. Ja; Humowiecki, Joel J.; Grönberg, Henrik; Chute, Christopher C.; Law, May M.; Kullo, Iftikar I.; Arnloev, Johan; Koenig, Barbara B.; Bielinski, Suzette S.; Pathak, Jyotishman J.; Henriksen, Joan J.; Blueher, Matthias; Ding, Keyue K.; Boettcher, Yvonne; Hart, Lacey L.; Palbicki, Jeremy J.; Larson, Eric B. Eb; Newton, Katherine K.; Ludman, Evette E.; Hart, Gene G.; Carrell, David D.; Jarvik, Gail G.; Crane, Paul P.; Burke, Wylie W.; Fullerton, Stephanie Malia SM; Carlson, Chris C.; Hutchinson, Fred F.; McDavid, Andrew A.; Dörr, Marcus; Doerr, Marcus; Clayton, Ellen E.; Haines, Jonathan L. Jl; Arnlov, Johan; Masys, Daniel R. Dr; Churchill, Larry R. Lr; Cornfield, Daniel D.; Arveiler, Dominique D.; Gräßler, Jürgen; Bakker, Stephan Jl L. Sj; Graessler, Juergen; Beilby, John J.; Groenberg, Henrik; Bergman, Richard N.; Crawford, Dana D.; Bergmann, Sven S.; Mckenzie, Colin A.; Biffar, Reiner R.; Gronberg, Henrik; Blangero, John J.; Darbar, Dawood D.; Boomsma, Dorret I. Di; Mclachlan, Stela; Bornstein, Stefan R.; Malin, Bradley A.; Bovet, Pascal P.; Denny, Joshua C. Jc; Brambilla, Paolo P.; Bottcher, Yvonne; Brown, Morris J. Mj; Müller, Gabriele; Campbell, Harry H.; Müller-Nurasyid, Martina; Caulfield, Mark J. Mj; Basford, Melissa M.; Chakravarti, Aravinda A.; Collins, Rory R.; Alizadeh, Behrooz Z. B.; Collins, Francis S. Fs; Boezen, H. Marike HM; Crawford, Dana C. Dc; Navis, Gerjan G.; Cupples, La Adrienne LA; Ormel, Johan J.; Danesh, John J.; Kho, An N.; Lindstroem, Jaana; De Faire, Ulf; Kathiresan, Sekar S.; Den Ruijter, Hm M.; Erbel, Raimund R.; Ardissino, Diego D.; Erdmann, Jeanette J.; Musunuru, Kiran K.; Eriksson, Johan G. Jg; Mannucci, Pier M. Pm; Farrall, Martin M.; Anand, Sonia S.; Ferrannini, Ele E.; Ferrières, Jean J.; Engert, James C. Jc; Ford, Ian I.; Mueller, Gabriele; Forouhi, Nita G. Ng; Morgan, Thomas T.; Forrester, Terrence T.; Mueller-Nurasyid, Martina; Gansevoort, Ron T. Rt; Kho, Abel An; Gejman, Pablo V. Pv; Girelli, Domenico D.; Gieger, Christian C.; Golay, Alain A.; Noethen, Markus M.; Gottesman, Omri O.; McKeown, Pascal P. Pp; Gudnason, Vilmundur; Gyllensten, Ulf U.; Patterson, Chris C. Cc; Haas, David W. Dw; Muller, Gabriele; Hall, Alistair S. As; Nothen, Markus Mm; Consortium, Electronic Medical Records and Genomics (eMEMERGEGE); Harris, Tamara B. Tb; Hattersley, Andrew T. At; Muller-Nurasyid, Martina; Heath, Andrew C. Ac; O'Donnell, Christopher J. Cj; Hengstenberg, Christian C.; Elosua, Roberto R.; Hicks, Andrew A. Aa; Melander, Olle O.; Hindorff, Lucia A. La; Hingorani, Aroon D. Ad; Merlini, Pier Angelica PA; Hofman, Albert A.; Altshuler, David D.; Hovingh, Gk Kees GK; Berzuini, Carlo C.; Humphries, Steve E. Se; H. Vermeulen, Sita; Hunt, Steven C. Sc; Ferrario, Maurizio M.; Hypponen, Elina E.; Bernardinelli, Luisa L.; Jacobs, Kevin B. Kb; Celli, Patrizia P.; Jarvelin, Marjo-Riitta Mr; Marziliano, Nicola N.; Jousilahti, Pekka P.; Fetiveau, Raffaela R.; Jula, Antti M. Am; Casari, Giorgio G.; Kaprio, Jaakko J.; Galli, Michele M.; Kastelein, John Jp P. Jj; Bernardi, Francesco F.; Kayser, Manfred M.; Kee, Frank F.; Friedlander, Yechiel Y.; Keinanen-Kiukaanniemi, Sirkka M. Sm; Lucas, Gavin G.; Kiemeney, Lambertus A. La; Marrugat, Jaume J.; Kooner, Jaspal S. Js; Meigs, James B. Jb; Kooperberg, Charles C.; Nathan, David M. Dm; Koskinen, Seppo S.; Havulinna, Aki S. As; Kovacs, Peter P.; Kraja, Aldi T. At; Duga, Stefano S.; Kumari, Meena M.; MacRae, Calum A. Ca; Kuusisto, Johanna J.; Berglund, Goran G.; Lakka, Timo A. Ta; Asselta, Rosanna R.; Langenberg, Claudia C.; Korn, Joshua M. Jm; Le Marchand, Loic L.; Lehtimäki, Terho T.; Nemesh, James J.; Lupoli, Sara S.; Daly, Mark J. Mj; Madden, Pamela Af F. Pa; Männistö, Satu S.; Ardissino, Diego D; Manunta, Paolo P.; Gianniny, Lauren L.; Marette, André Andre; Matise, Tara C. Tc; Guiducci, Candace C.; McKnight, Barbara B.; Ml, Buchkovich; Meitinger, Thomas T.; McCarroll, Steven A. Sa; Moll, Frans L. Fl; Montgomery, Grant W. Gw; Parkin, Melissa M.; Morris, Andrew D. Ad; Morris, Andrew P. Ap; Murray, Jeffrey C. Jc; Burtt, Noel N.; Nelis, Mari M.; Gabriel, Stacey B. Sb; Ohlsson, Claes C.; Oldehinkel, Albertine J. Aj; Mirel, Daniel D.; Ong, Ken K. Kk; Braund, Peter S. Ps; Ouwehand, Willem H. Wh; Peters, Annette A.; Adrienne Cupples, L.; Pasterkamp, Gerard G.; Loic, Le Marchandm; Pramstaller, Peter P. Pp; Mannucci, Pier M Pm; Elosua, Roberto R; Balmforth, Anthony J. Aj; Ball, Stephen G. Sg; Kathiresan, Sekar S; Linsel-Nitschke, Patrick P.; Lieb, Wolfgang W.; O'Donnell, Christopher J Cj; Fischer, Marcus M.; Melander, Olle O; König, Inke R. Ir; Dc, Croteau Chonka; Grosshennig, Anika A.; Kees Hovingh, G.; Hayes, Mg Geoffrey MG; Ks, Lo; Musunuru, Kiran K; Goodall, Alison A.; Ouwehand, Willem W.; Männistö, Satu; Cambien, Francois F.; Mcknight, Barbara; Ae, Locke; Lucas, Gavin G; Marchand, Loic Le; Chen, Zhen Z.; Li, Mingyao M.; Mannisto, Satu; Matthai, William W.; Amouyel, Philippe P.; Laan, S. W. van der; Asselbergs, Folkert W. Fw; Hakonarson, Hakon H. Hh; Assimes, Themistocles L. Tl; Kent, Kenneth M. Km; Bochud, Murielle Murille; Devaney, Joe J.; Boehm, Bernhard O. Bo; Burnett, Mary-Susan; Boerwinkle, Eric E.; Knouff, Christopher W. Cw; Bottinger, Erwin P. Ep; Lindsay, Joseph M. Jm; Bouchard, Claude C.; De Bakker, Piw I. W.; Cauchi, Stéphane Stephane; König, Inke R. I.; Chambers, John C. Jc; Mooser, Vincent; Chanock, Stephen J. Sj; Cooper, Richard S. Rs; Fr, Day; Dedoussis, George G.; Medical, Records The Electronic; Genomics, Consortium; Ferrucci, Luigi L.; Hayes, Mg Geoff M.; Franks, Paul W. Pw; Epstein, Stephen E. Se; Froguel, Philippe P.; Cohort, Study The LifeLines; Groop, Leif C. Lc; Hólm, Hilma H.; Haiman, Christopher A. Ca; Do, Ron R.; Hamsten, Anders A.; Berger, Klaus K.; Hui, Jennie J.; Hunter, David J. Dj; ..,; Hveem, Kristian K.; Higashio, Julia J.; Jukema, Jw Wouter JW; Kaplan, Robert C. Rc; Matise, Tara T.; Kivimaki, Mika M.; Au, Jackson; Kuh, Diana D.; Laakso, Markku M.; Nato, Andrew A.; Liu, Yongmei Ym; Hindorff, Lucia L.; Martin, Nicholas G. Ng; Linsel-Nitschke, Patrick P; März, Winfried W.; Melbye, Mads M.; Manolio, Teri T.; Huge, Andreas A.; Moebus, Susanne S.; Munroe, Patricia B. Pb; Lieb, Wolfgang W; Njølstad, Inger I.; Heiss, Gerardo G.; Pedersen, Nancy L. Nl; Geoffrey Hayes, M.; Oostra, Ben A.; Palmer, Colin Na A. Cn; Fischer, Marcus M; Perola, Markus M.; Ambite, Jose Luis JL; Consortium, MIGen; Patterson, Chris C Cc; Peters, Ulrike U.; McKeown, Pascal P Pp; Powell, Joseph E. Je; Franceschini, Nora N.; Power, Chris C.; Grosshennig, Anika A; Deelman, Ewa E.; März, Winfried; Martinelli, Nicola N.; Corrocher, Roberto R.; Marz, Winfried; Olivieri, Oliviero O.; Avery, Christy C.; Engert, James C Jc; Maerz, Winfried; Lin, Danyu D.; Anand, Sonia S; Eline Slagboom, P.; Graff, Misa M.; Cochran, Barbara B.; MacCluer, Jean J.; Cole, Shelley S.; Pankow, James J.; Altshuler, David D; Gross, Myron M.; Jenny, Nancy N.; Fornage, Myriam M.; Arnold, Alice A.; Erich Wichmann, H.; Durda, Peter P.; Patsy, Bruce B.; Kao, Linda L.; Murdock, Deborah D.; Haines, Jonathan J.; Glenn, Kim K.; Buzkova, Petra P.; Bush, William S. Ws; Deloukas, Panos P.; Heid, Iris M. Im; Boston, Jonathan J.; Lindgren, Cecilia M. Cm; Goodloe, Robert R.; Malinowski, Jennifer J.; Mohlke, Karen L. Kl; Crawford, Dana D; Oetjens, Matthew M.; Fowke, Jay J.; Barroso, Inês Inês; Jong, P. A. de; Fox, Caroline S. Cs; Kolonel, Laurence L.; North, Kari E. Ke; Cheng, Iona I.; Beckmann, Jacques S. Js; Park, Lani L.; Berndt, Sonja I. Si; Dumitrescu, Logan L.; Boehnke, Michael M.; Borecki, Ingrid B. Ib; McCarthy, Mark I. Mi; Brown-Gentry, Kristin K.; Haiman, Christopher C.; Metspalu, Andres A.; Mitchell, Sabrina L. Sl; Henderson, Brian B.; Monroe, Kristine K.; Anderson, Garnet G.; LaCroix, Andrea A.; Franke, Lude L.; Carlson, Chris C; O’connell, Jeffrey R.; Price, Alkes L. Al; Carty, Cara C.; Kocarnik, Jonathan J.; Lettre, Guillaume G.; Loos, Ruth Jf F. Rj; Lin, Yi Y.; Elect Med Records &amp; Genom eMERGE, C.; Jackson, Rebecca R.; Ingelsson, Erik E.; &amp;amp, Elect Med Records; O'Connell, Jeffrey R.; Duggan, David D.; Abecasis, Goncalo R. Gr; Genom eMERGE, C.; Chasman, Daniel I. Di; Page, Consortium; Goddard, Michael E. Me; Ja, Spertus; Kuller, Lew L.; Hirschhorn, Joel N. Jn; Frayling, Timothy M. Tm; Other, And; Others,; Price, Jackie

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Jian Yang
Ärnl et al., 2014

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@article{Ärnl2014,
  abstract = {Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated approximately 2,000, approximately 3,700 and approximately 9,500 SNPs explained approximately 21%, approximately 24% and approximately 29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes and pathways not highlighted in earlier efforts, such as signaling by fibroblast growth factors, WNT/beta-catenin and chondroitin sulfate-related genes. We identified several genes and pathways not previously connected with human skeletal growth, including mTOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number (thousands) of causal variants.},
  author = {Ärnl, Johan and de Andrade, Mariza M. and de Boer, Rudolf A. Ra and van der Klauw, Melanie M. Mm and den Ruijter Hester, M. and Zonzin, Pietro P. and Ziegler, Andreas A. and de Bakker Paul, I. W. and Ziegler, Andreas A and Zheng, Wei W. and van Duijn Cornelia, M. and Zhang, Weihua W. and Yee, Jean J. and Yee, Jean J and Young, Alicia A. and Wood, Andrew R. Ar and Zhao, Jing Hua JH and Wang, Zhaoming Z and Yang, Jian J. and Wang, Zhaoming Z. and Schumacher, Fredrick R. and Schumacher, Fredrick R. Fr and Wilkens, Lynne R. and Wang, Zhaoming and Wilkens, Lynne R. Lr and Randall, Joshua C. Jc and Scherag, André Andre and Ritchie, Marylyn M. and Vinkhuyzen, Anna Ae E. Aa and Vedantam, Sailaja S. and Westra, Harm-Jan Hj and Starren, Justin J. and Winkler, Thomas W. Tw and Workalemahu, Tsegaselassie T. and Wang, Z. and Rasmussen, Luke L. and Waudby, Carol C. and Reeser, Jonathan J. and Wilke, Russell A. Ra and Smith, Maureen E. Me and Wolf, Wendy A. Wa and Thompson, William K. Wk and van der Laan, Sander W. Sw and van Setten, Jessica J. and Wang, Zm and Savova, Guergana G. and Yengo, Loïc Loïc and Wu, Joel J. and Zhang, Weihua and Wolfgang, Hoffmannm and Ärnlöv, Johan and Spangler, Leslie L. and Trinidad, Susan Brown SB and Roden, Dan M. Dm and Warwick Daw, E. and Schildcrout, Jonathan S. Js and Xu, Hua H. and Ramirez, Andrea Havens AH and Pulley, Jill J. and Rosmalen, Judith G. M. Jg and Slaets, Joris P. Jp and Wolffenbuttel, Bruce H. R. Bh and Wijmenga, Cisca C. and Voight, Benjamin F. Bf and Purcell, Shaun S. and Ritchie, Marylyn M and Prokopenko, Inga I. and Reilly, Muredach P. and de Groot, Lisette C. P. G. M. Lc and Ried, Janina S. Js and Rader, Daniel J. Dj and Van Vliet-Ostaptchouk, Jana V. Jv and Ripke, Stephan S. and Spertus, John A. Ja and Shungin, Dmitry D. and Stoll, Monika M. and Stancáková, Alena A. and Strawbridge, Rona J. Rj and Siscovick, David S. Ds and Sung, Yun Ju YJ and Tanaka, Toshiko T. and Shin, Jianxin and Teumer, Alexander A. and Trompet, Stella S. and Schwartz, Stephen M. Sm and Tubaro, Marco M. and Ribichini, Flavio F. and Rossi, Marco M. and Van Der Laan, Sander W. and Van Vliet-Ostaptchouk, Jv and Subirana, Isaac I. and Ramos, Rafael R. and Sala, Joan J. and Williams, Gordon G. and Voight, Benjamin F. B. and Schunkert, I. Heribert I and Spreafico, Marta M. and Surti, Aarti A. and Thompson, John R. and Schwartz, Stephen M Sm and Siscovick, David S Ds and Schumacher, Fredrick Fr and Wright, Benjamin J. Bj and Stark, Klaus K. and Schreiber, Stefan S. and Purcell, Shaun S and Voight, Benjamin F Bf and Wilkens, Lynne Lr and Scholz, Michael M. and Subirana, Isaac I and Wilensky, Robert R. and Setten, J. van and Qasim, Atif A. and Vliet-Ostaptchouk, J. V. Van and Waksman, Ron R. and Satler, Lowell L. and Walker, Max C. Mc and Waterworth, Dawn M. Dm and Scheffold, Thomas T. and The, MIGen Consortium and van Dijk, Suzanne S. and The, Page Consortium and van Schoor, Natasja M. Nm and Xie, Changchun C. and van der Velde, Nathalie and van Heemst, Diana D. and Tönjes, Anke and van Oort, Floor Va A. Fv and Toenjes, Anke and Siscovick, David D. and Rader, Daniel J Dj and Williams, Rasheeda R. and Wouter Jukema, J. and Spertus, John A Ja and Stark, Klaus K and Zhang, Qunyuan Qy and Taylor, Kira K. and Th, Pers and Schreiber, Stefan S and Quibrera, Miguel M. and de Faire, Ulf U. and Volzke, Henry and den Ruijter, Hester M. Hm and Voelzke, Henry and Thornton-Wells, Tricia T. and Restrepo, Nicole N. and Umans, Jason J. and Wilson, Sarah S. and Spencer, Kylee K. and Wang, Hansong H. and Shohet, Ralph R. and Stram, Daniel D. and Tiirikainen, Maarit M. and Wu, Chunyuan C. and Rosse, Stephanie S. and Study, LifeLines Cohort and Rayner, Nigel W. Nw and Renstrom, Frida F. and Robertson, Neil R. Nr and Rose, Lynda M. Lm and Roussel, Ronan R. and Schumacher, Fr R. and Sanna, Serena S. and Scharnagl, Hubert H. and Scholtens, Salome S. and de Bakker, Paul Iw W. Pi and Schunkert, Heribert H. and Scott, Robert A. Ra and Sehmi, Joban J. and Seufferlein, Thomas T. and Shi, Jianxin J. and Silventoinen, Karri K. and Smit, Johannes H. Jh and Smith, Albert Vernon AV and Smolonska, Joanna J. and Stanton, Alice V. Av and Stirrups, Kathleen K. and Stott, David J. Dj and Stringham, Heather M. Hm and Sundström, Johan J. and Swertz, Morris A. and Syvänen, Ann-Christine Ac and Tayo, Bamidele O. Bo and Van Dijk, Suzanne and Thorleifsson, Gudmar G. and Van Schoor, Natasja M. and Tyrer, Jonathan P. Jp and Van Der Velde, N. and Van Heemst, Diana and Van Oort, Floor V. A. and van der Harst, Pim P. and Vermeulen, Sita H. Sh and Verweij, Niek N. and Vonk, Judith M. Jm and Zanen, Pieter P. and Waite, Lindsay L. Ll and Waldenberger, Melanie M. and Wilkens, Lr R. and Wennauer, Roman R. and Willenborg, Christina C. and Wilsgaard, Tom T. and Wojczynski, Mary K. Mk and Wong, Andrew A. and Wright, Alan F. Af and van Duijn, Cornelia M. Cm and Price, Jackie F. Jf and Qi, Lu L. and Raitakari, Olli T. Ot and Rankinen, Tuomo T. and Rao, Dc C. Dc and Rice, Treva K. Tk and Ritchie, Marylyn D. and Rudan, Igor I. and Salomaa, Veikko and Samani, Nilesh J. Nj and Saramies, Jouko J. and Sarzynski, Mark A. and Schwarz, Peter Eh H. Pe and Sebert, Sylvain S. and Sever, Peter P. and Shuldiner, Alan R. Ar and Sinisalo, Juha J. and Steinthorsdottir, Valgerdur and Stolk, Ronald P. Rp and Tardif, Jean-Claude Jc and Tönjes, Anke A. and Tremblay, Angelo A. and Tremoli, Elena E. and Virtamo, Jarmo J. and Vohl, Marie-Claude Mc and Tm, Frayling and Pérusse, Louis L. and Quertermous, Thomas T. and Rauramaa, Rainer R. and Reinmaa, Eva E. and Ridker, Paul M. Pm and Rivadeneira, Fernando F. and Rotter, Jerome I. Ji and Saaristo, Timo E. Te and Saleheen, Danish D. and Schlessinger, David D. and Slagboom, Pe Eline PE and Snieder, Harold H. and Van Der Harst, Pim and Spector, Tim D. Td and Strauch, Konstantin K. and Stumvoll, Michael M. and Tuomilehto, Jaakko J. and Uusitupa, Matti M. and Völzke, Henry H. and Walker, Mark M. and Wareham, Nicholas J. Nj and Watkins, Hugh H. and Wichmann, He-Erich He and Wilson, James F. Jf and Speliotes, Elizabeth K. Ek and Thorsteinsdottir, Unnur U. and Strachan, David P. Dp and Van Duijn, Cm M. and Stefansson, Kari K. and Uitterlinden, André G. Ag and Willer, Cristen J. Cj and Weedon, Michael N. Mn and Visscher, Peter M. Pm and Pers, Tune H. Th and Chu, Audrey Y. Ay and Buchkovich, Martin L. Ml and Esko, Tonu Tõnu and Croteau-Chonka, Damien C. Dc and Day, Felix R. Fr and Jackson, Anne U. Au and Lo, Ken Sin KS and Locke, Adam E. Ae and Mägi, Reedik R. and Porcu, Eleonora Evelin and Mihailov, Evelin E. and Peissig, Peggy P. and Absher, Devin D. and Albrecht, Eva E. and Anderson, Denise D. and Baron, Jeffrey J. and Beekman, Marian M. and Demirkan, Ayse Ayşe and Ehret, Georg Benedikt Gb and Gustafsson, Stefan S. and Feenstra, Bjarke B. and Feitosa, Mary F. and Fischer, Krista K. and Fraser, Ross M. Rm and Goel, Anuj A. and Gong, Jian J. and Kanoni, Stavroula S. and Kleber, Marcus E. Me and Kristiansson, Kati K. and Ar, Wood and Lim, Unhee U. and A. E., Justice and Lotay, Vaneet and Lui, Julian C. Jc and Mangino, Massimo M. and Postma, Dirkje S. Ds and Estrada, Karol K. and Medina-Gomez, Carolina C. and Nalls, Michael A. and Nyholt, Dale R. Dr and Leach, Im M. and Palmer, Cameron D. Cd and Luan, Jian'An Jian’an and Pasko, Dorota D. and Pechlivanis, Sonali S. and Kutalik, Zoltán Zoltán and Peltonen, Leena L. and Peyvandi, Flora F. and Amin, Najaf N. and Justice, Anne E. and Afzal, Uzma U. and Piazza, Alberto A. and Arscott, Gillian M. Gm and Bandinelli, Stefania S. and Barrett, Amy A. and Bellis, Claire C. and Bennett, Amanda J. Aj and Berne, Christian C. and Blüher, Matthias M. and Bolton, Jennifer L. Jl and Böttcher, Yvonne Y. and Boyd, Heather A. Ha and Bruinenberg, Marcel M. and Peltonen, Leena L and Buckley, Brendan M. Bm and Preuss, Michael M. and Buyske, Steve Steven and Caspersen, Ida H. Ih and Chines, Peter S. Ps and Duan, Yanan Y. and Clarke, Robert R. and Claudi-Boehm, Simone S. and Cooper, Matthew M. and Daw, Ew Warwick EW and De Jong, Pim A. Pa and Deelen, Joris J. and Fall, Tove T. and Delgado, Graciela G. and Denny, Josh C. Jc and Pichard, Augusto D. Ad and Dhonukshe-Rutten, Rosalie R. and Dimitriou, Maria M. and Doney, Alex Sf F. As and Dörr, Marcus M. and Fehrmann, Rudolf R. and Eklund, Niina N. and Eury, Elodie E. and Folkersen, Lasse L. and Garcia, Melissa E. Me and Geller, Frank F. and Giedraitis, Vilmantas and Go, Alan S. As and Ferreira, Teresa T. and Grallert, Harald H. and Grammer, Tanja B. Tb and Gräßler, Jürgen J. and Grönberg, Henrik H. and Groves, Christopher J. Cj and Haessler, Jeff Jeffrey and Hall, Per and De Groot, Lisette C. P. G. M. and Haller, Toomas T. and Preuss, Michael M and Hallmans, Goran Göran and Hannemann, Anke A. and Karjalainen, Juha J. and Hartman, Catharina A. Ca and Hassinen, Maija M. and Perusse, Louis and Hayward, Caroline C. and Pérusse, Louis and Heard-Costa, Nancy L. Nl and Helmer, Quinta Q. and Person, Sharina S. and Hemani, Gibran G. and Henders, Anjali K. Ak and Hillege, Hans L. Hl and Hlatky, Mark A. and Hoffmann, Wolfgang W. and Hoffmann, Per P. and Holmen, Oddgeir O. and Houwing-Duistermaat, Jeanine J. Jj and Pendergrass, Sarah S. and Illig, Thomas T. and Isaacs, Aaron A. and James, Alan L. Al and Jeff, Janina Jarina and Johansen, Berit Bent and Jolley, Jennifer J. and Johansson, Å. and Juliusdottir, Thorhildur T. and Junttila, Juhani J. and Prentice, Ross R. and Kho, Abel N. and Kinnunen, Leena L. and Klopp, Norman N. and Kocher, Thomas T. and Chun, Audrey Y. and Kratzer, Wolfgang W. and Ae, Anne E. and Lichtner, Peter P. and Johansson, Åsa Å and Lind, Lars L. and Buyske, Steven S. and Lindström, Jaana J. and Mägi, Reedik and Lobbens, Stéphane Stéphane and Haessler, Jeffrey J. and Lorentzon, Mattias Matthias and Hall, Per P. and Lu, Yingchang Yc and Lyssenko, Valeriya and Kho, Abel N. An and Magnusson, Patrik Ke E. Pk and Maegi, Reedik and Mahajan, Anubha A. and Ae, Justice and Maillard, Marc M. and Magi, Reedik and McArdle, Wendy L. Wl and Pagege, Consortium and McKenzie, Colin A. Ca and Ju Sung, Yun and McLachlan, Stela S. and McLaren, Paul J. Pj and McCarty, Catherine A. Ca and Menni, Cristina C. and Johansson, Åsa and Berg, Richard R. and Merger, Sigrun S. and Milani, Lili L. and Moayyeri, Alireza A. and Linneman, James J. and Monda, Keri L. Kl and Böttcher, Yvonne and Morken, Mario A. and Miller, Aaron A. and Müller, Gabriele G. and Müller-Nurasyid, Martina M. and E., Anne and Musk, Arthur W. Aw and Choudary, Vidhu and Narisu, Narisu N. and Nauck, Matthias M. and Nolte, Ilja M. Im and Chen, Lin L. and Nöthen, Markus M. Mm and Pilz, Stefan S. and Oozageer, Laticia L. and Kitchner, Terrie T. and Mateo Leach, Irene I. and Fost, Norman N. and Chisholm, Rex L. Rl and Avila, Pedro C. Pc and Greenland, Philip P. and Ay, Chu and Arnl, Johan J. and Kibbe, Warren A. Wa and Lemke, Amy A. Aa and Lowe, William L. Wl and Pacheco, Jennifer A. Ja and Humowiecki, Joel J. and Grönberg, Henrik and Chute, Christopher C. and Law, May M. and Kullo, Iftikar I. and Arnloev, Johan and Koenig, Barbara B. and Bielinski, Suzette S. and Pathak, Jyotishman J. and Henriksen, Joan J. and Blueher, Matthias and Ding, Keyue K. and Boettcher, Yvonne and Hart, Lacey L. and Palbicki, Jeremy J. and Larson, Eric B. Eb and Newton, Katherine K. and Ludman, Evette E. and Hart, Gene G. and Carrell, David D. and Jarvik, Gail G. and Crane, Paul P. and Burke, Wylie W. and Fullerton, Stephanie Malia SM and Carlson, Chris C. and Hutchinson, Fred F. and McDavid, Andrew A. and Dörr, Marcus and Doerr, Marcus and Clayton, Ellen E. and Haines, Jonathan L. Jl and Arnlov, Johan and Masys, Daniel R. Dr and Churchill, Larry R. Lr and Cornfield, Daniel D. and Arveiler, Dominique D. and Gräßler, Jürgen and Bakker, Stephan Jl L. Sj and Graessler, Juergen and Beilby, John J. and Groenberg, Henrik and Bergman, Richard N. and Crawford, Dana D. and Bergmann, Sven S. and Mckenzie, Colin A. and Biffar, Reiner R. and Gronberg, Henrik and Blangero, John J. and Darbar, Dawood D. and Boomsma, Dorret I. Di and Mclachlan, Stela and Bornstein, Stefan R. and Malin, Bradley A. and Bovet, Pascal P. and Denny, Joshua C. Jc and Brambilla, Paolo P. and Bottcher, Yvonne and Brown, Morris J. Mj and Müller, Gabriele and Campbell, Harry H. and Müller-Nurasyid, Martina and Caulfield, Mark J. Mj and Basford, Melissa M. and Chakravarti, Aravinda A. and Collins, Rory R. and Alizadeh, Behrooz Z. B. and Collins, Francis S. Fs and Boezen, H. Marike HM and Crawford, Dana C. Dc and Navis, Gerjan G. and Cupples, La Adrienne LA and Ormel, Johan J. and Danesh, John J. and Kho, An N. and Lindstroem, Jaana and De Faire, Ulf and Kathiresan, Sekar S. and Den Ruijter, Hm M. and Erbel, Raimund R. and Ardissino, Diego D. and Erdmann, Jeanette J. and Musunuru, Kiran K. and Eriksson, Johan G. Jg and Mannucci, Pier M. Pm and Farrall, Martin M. and Anand, Sonia S. and Ferrannini, Ele E. and Ferrières, Jean J. and Engert, James C. Jc and Ford, Ian I. and Mueller, Gabriele and Forouhi, Nita G. Ng and Morgan, Thomas T. and Forrester, Terrence T. and Mueller-Nurasyid, Martina and Gansevoort, Ron T. Rt and Kho, Abel An and Gejman, Pablo V. Pv and Girelli, Domenico D. and Gieger, Christian C. and Golay, Alain A. and Noethen, Markus M. and Gottesman, Omri O. and McKeown, Pascal P. Pp and Gudnason, Vilmundur and Gyllensten, Ulf U. and Patterson, Chris C. Cc and Haas, David W. Dw and Muller, Gabriele and Hall, Alistair S. As and Nothen, Markus Mm and Consortium, Electronic Medical Records and Genomics (eMEMERGEGE) and Harris, Tamara B. Tb and Hattersley, Andrew T. At and Muller-Nurasyid, Martina and Heath, Andrew C. Ac and O'Donnell, Christopher J. Cj and Hengstenberg, Christian C. and Elosua, Roberto R. and Hicks, Andrew A. Aa and Melander, Olle O. and Hindorff, Lucia A. La and Hingorani, Aroon D. Ad and Merlini, Pier Angelica PA and Hofman, Albert A. and Altshuler, David D. and Hovingh, Gk Kees GK and Berzuini, Carlo C. and Humphries, Steve E. Se and H. Vermeulen, Sita and Hunt, Steven C. Sc and Ferrario, Maurizio M. and Hypponen, Elina E. and Bernardinelli, Luisa L. and Jacobs, Kevin B. Kb and Celli, Patrizia P. and Jarvelin, Marjo-Riitta Mr and Marziliano, Nicola N. and Jousilahti, Pekka P. and Fetiveau, Raffaela R. and Jula, Antti M. Am and Casari, Giorgio G. and Kaprio, Jaakko J. and Galli, Michele M. and Kastelein, John Jp P. Jj and Bernardi, Francesco F. and Kayser, Manfred M. and Kee, Frank F. and Friedlander, Yechiel Y. and Keinanen-Kiukaanniemi, Sirkka M. Sm and Lucas, Gavin G. and Kiemeney, Lambertus A. La and Marrugat, Jaume J. and Kooner, Jaspal S. Js and Meigs, James B. Jb and Kooperberg, Charles C. and Nathan, David M. Dm and Koskinen, Seppo S. and Havulinna, Aki S. As and Kovacs, Peter P. and Kraja, Aldi T. At and Duga, Stefano S. and Kumari, Meena M. and MacRae, Calum A. Ca and Kuusisto, Johanna J. and Berglund, Goran G. and Lakka, Timo A. Ta and Asselta, Rosanna R. and Langenberg, Claudia C. and Korn, Joshua M. Jm and Le Marchand, Loic L. and Lehtimäki, Terho T. and Nemesh, James J. and Lupoli, Sara S. and Daly, Mark J. Mj and Madden, Pamela Af F. Pa and Männistö, Satu S. and Ardissino, Diego D and Manunta, Paolo P. and Gianniny, Lauren L. and Marette, André Andre and Matise, Tara C. Tc and Guiducci, Candace C. and McKnight, Barbara B. and Ml, Buchkovich and Meitinger, Thomas T. and McCarroll, Steven A. Sa and Moll, Frans L. Fl and Montgomery, Grant W. Gw and Parkin, Melissa M. and Morris, Andrew D. Ad and Morris, Andrew P. Ap and Murray, Jeffrey C. Jc and Burtt, Noel N. and Nelis, Mari M. and Gabriel, Stacey B. Sb and Ohlsson, Claes C. and Oldehinkel, Albertine J. Aj and Mirel, Daniel D. and Ong, Ken K. Kk and Braund, Peter S. Ps and Ouwehand, Willem H. Wh and Peters, Annette A. and Adrienne Cupples, L. and Pasterkamp, Gerard G. and Loic, Le Marchandm and Pramstaller, Peter P. Pp and Mannucci, Pier M Pm and Elosua, Roberto R and Balmforth, Anthony J. Aj and Ball, Stephen G. Sg and Kathiresan, Sekar S and Linsel-Nitschke, Patrick P. and Lieb, Wolfgang W. and O'Donnell, Christopher J Cj and Fischer, Marcus M. and Melander, Olle O and König, Inke R. Ir and Dc, Croteau Chonka and Grosshennig, Anika A. and Kees Hovingh, G. and Hayes, Mg Geoffrey MG and Ks, Lo and Musunuru, Kiran K and Goodall, Alison A. and Ouwehand, Willem W. and Männistö, Satu and Cambien, Francois F. and Mcknight, Barbara and Ae, Locke and Lucas, Gavin G and Marchand, Loic Le and Chen, Zhen Z. and Li, Mingyao M. and Mannisto, Satu and Matthai, William W. and Amouyel, Philippe P. and Laan, S. W. van der and Asselbergs, Folkert W. Fw and Hakonarson, Hakon H. Hh and Assimes, Themistocles L. Tl and Kent, Kenneth M. Km and Bochud, Murielle Murille and Devaney, Joe J. and Boehm, Bernhard O. Bo and Burnett, Mary-Susan and Boerwinkle, Eric E. and Knouff, Christopher W. Cw and Bottinger, Erwin P. Ep and Lindsay, Joseph M. Jm and Bouchard, Claude C. and De Bakker, Piw I. W. and Cauchi, Stéphane Stephane and König, Inke R. I. and Chambers, John C. Jc and Mooser, Vincent and Chanock, Stephen J. Sj and Cooper, Richard S. Rs and Fr, Day and Dedoussis, George G. and Medical, Records The Electronic and Genomics, Consortium and Ferrucci, Luigi L. and Hayes, Mg Geoff M. and Franks, Paul W. Pw and Epstein, Stephen E. Se and Froguel, Philippe P. and Cohort, Study The LifeLines and Groop, Leif C. Lc and Hólm, Hilma H. and Haiman, Christopher A. Ca and Do, Ron R. and Hamsten, Anders A. and Berger, Klaus K. and Hui, Jennie J. and Hunter, David J. Dj and ..,  and Hveem, Kristian K. and Higashio, Julia J. and Jukema, Jw Wouter JW and Kaplan, Robert C. Rc and Matise, Tara T. and Kivimaki, Mika M. and Au, Jackson and Kuh, Diana D. and Laakso, Markku M. and Nato, Andrew A. and Liu, Yongmei Ym and Hindorff, Lucia L. and Martin, Nicholas G. Ng and Linsel-Nitschke, Patrick P and März, Winfried W. and Melbye, Mads M. and Manolio, Teri T. and Huge, Andreas A. and Moebus, Susanne S. and Munroe, Patricia B. Pb and Lieb, Wolfgang W and Njølstad, Inger I. and Heiss, Gerardo G. and Pedersen, Nancy L. Nl and Geoffrey Hayes, M. and Oostra, Ben A. and Palmer, Colin Na A. Cn and Fischer, Marcus M and Perola, Markus M. and Ambite, Jose Luis JL and Consortium, MIGen and Patterson, Chris C Cc and Peters, Ulrike U. and McKeown, Pascal P Pp and Powell, Joseph E. Je and Franceschini, Nora N. and Power, Chris C. and Grosshennig, Anika A and Deelman, Ewa E. and März, Winfried and Martinelli, Nicola N. and Corrocher, Roberto R. and Marz, Winfried and Olivieri, Oliviero O. and Avery, Christy C. and Engert, James C Jc and Maerz, Winfried and Lin, Danyu D. and Anand, Sonia S and Eline Slagboom, P. and Graff, Misa M. and Cochran, Barbara B. and MacCluer, Jean J. and Cole, Shelley S. and Pankow, James J. and Altshuler, David D and Gross, Myron M. and Jenny, Nancy N. and Fornage, Myriam M. and Arnold, Alice A. and Erich Wichmann, H. and Durda, Peter P. and Patsy, Bruce B. and Kao, Linda L. and Murdock, Deborah D. and Haines, Jonathan J. and Glenn, Kim K. and Buzkova, Petra P. and Bush, William S. Ws and Deloukas, Panos P. and Heid, Iris M. Im and Boston, Jonathan J. and Lindgren, Cecilia M. Cm and Goodloe, Robert R. and Malinowski, Jennifer J. and Mohlke, Karen L. Kl and Crawford, Dana D and Oetjens, Matthew M. and Fowke, Jay J. and Barroso, Inês Inês and Jong, P. A. de and Fox, Caroline S. Cs and Kolonel, Laurence L. and North, Kari E. Ke and Cheng, Iona I. and Beckmann, Jacques S. Js and Park, Lani L. and Berndt, Sonja I. Si and Dumitrescu, Logan L. and Boehnke, Michael M. and Borecki, Ingrid B. Ib and McCarthy, Mark I. Mi and Brown-Gentry, Kristin K. and Haiman, Christopher C. and Metspalu, Andres A. and Mitchell, Sabrina L. Sl and Henderson, Brian B. and Monroe, Kristine K. and Anderson, Garnet G. and LaCroix, Andrea A. and Franke, Lude L. and Carlson, Chris C and O’connell, Jeffrey R. and Price, Alkes L. Al and Carty, Cara C. and Kocarnik, Jonathan J. and Lettre, Guillaume G. and Loos, Ruth Jf F. Rj and Lin, Yi Y. and Elect Med Records &amp; Genom eMERGE, C. and Jackson, Rebecca R. and Ingelsson, Erik E. and &amp;amp, Elect Med Records and O'Connell, Jeffrey R. and Duggan, David D. and Abecasis, Goncalo R. Gr and Genom eMERGE, C. and Chasman, Daniel I. Di and Page, Consortium and Goddard, Michael E. Me and Ja, Spertus and Kuller, Lew L. and Hirschhorn, Joel N. Jn and Frayling, Timothy M. Tm and Other, And and Others,  and Price, Jackie},
  doi = {10.1038/ng.3097},
  month = {oct},
  title = {Defining the role of common variation in the genomic and biological architecture of adult human height.},
  url = {http://www.nature.com/articles/ng.3097.pdf},
  year = {2014}
}

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Defining the role of common variation in the genomic and biological architecture of adult human height.

Journal article published in 2014 by Johan Ärnl, Mariza M. de Andrade, Rudolf A. Ra de Boer, Melanie M. Mm van der Klauw, M. den Ruijter Hester, Pietro P. Zonzin, Andreas A. Ziegler, I. W. de Bakker Paul, Andreas A Ziegler, Wei W. Zheng, M. van Duijn Cornelia, Weihua W. Zhang, Jean J. Yee, Jean J Yee, Alicia A. Young and other authors. Johan Ärnl, Mariza M. de Andrade, Rudolf A. Ra de Boer, Melanie M. Mm van der Klauw, M. den Ruijter Hester, Pietro P. Zonzin, Andreas A. Ziegler, I. W. de Bakker Paul, Andreas A Ziegler, Wei W. Zheng, M. van Duijn Cornelia, Weihua W. Zhang, Jean J. Yee, Jean J Yee, Alicia A. Young, Andrew R. Ar Wood, Jing Hua JH Zhao, Zhaoming Z Wang, Jian J. Yang

, Zhaoming Z. Wang, Fredrick R. Schumacher, Fredrick R. Fr Schumacher, Lynne R. Wilkens, Zhaoming Wang, Lynne R. Lr Wilkens, Joshua C. Jc Randall, André Andre Scherag, Marylyn M. Ritchie, Anna Ae E. Aa Vinkhuyzen, Sailaja S. Vedantam, Harm-Jan Hj Westra, Justin J. Starren, Thomas W. Tw Winkler, Tsegaselassie T. Workalemahu, Z. Wang, Luke L. Rasmussen, Carol C. Waudby, Jonathan J. Reeser, Russell A. Ra Wilke, Maureen E. Me Smith, Wendy A. Wa Wolf, William K. Wk Thompson, Sander W. Sw van der Laan, Jessica J. van Setten, Zm Wang, Guergana G. Savova, Loïc Loïc Yengo, Joel J. Wu, Weihua Zhang, Hoffmannm Wolfgang, Johan Ärnlöv, Leslie L. Spangler, Susan Brown SB Trinidad, Dan M. Dm Roden, E. Warwick Daw, Jonathan S. Js Schildcrout, Hua H. Xu, Andrea Havens AH Ramirez, Jill J. Pulley, Judith G. M. Jg Rosmalen, Joris P. Jp Slaets, Bruce H. R. Bh Wolffenbuttel, Cisca C. Wijmenga, Benjamin F. Bf Voight, Shaun S. Purcell, Marylyn M Ritchie, Inga I. Prokopenko

, Muredach P. Reilly, Lisette C. P. G. M. Lc de Groot, Janina S. Js Ried, Daniel J. Dj Rader, Jana V. Jv Van Vliet-Ostaptchouk, Stephan S. Ripke, John A. Ja Spertus, Dmitry D. Shungin, Monika M. Stoll, Alena A. Stancáková, Rona J. Rj Strawbridge, David S. Ds Siscovick, Yun Ju YJ Sung, Toshiko T. Tanaka, Jianxin Shin, Alexander A. Teumer, Stella S. Trompet, Stephen M. Sm Schwartz, Marco M. Tubaro, Flavio F. Ribichini, Marco M. Rossi, Sander W. Van Der Laan, Jv Van Vliet-Ostaptchouk, Isaac I. Subirana, Rafael R. Ramos, Joan J. Sala, Gordon G. Williams, Benjamin F. B. Voight, I. Heribert I Schunkert, Marta M. Spreafico, Aarti A. Surti, John R. Thompson, Stephen M Sm Schwartz, David S Ds Siscovick, Fredrick Fr Schumacher, Benjamin J. Bj Wright, Klaus K. Stark, Stefan S. Schreiber, Shaun S Purcell, Benjamin F Bf Voight, Lynne Lr Wilkens, Michael M. Scholz, Isaac I Subirana, Robert R. Wilensky, J. van Setten, Atif A. Qasim, J. V. Van Vliet-Ostaptchouk, Ron R. Waksman, Lowell L. Satler, Max C. Mc Walker, Dawn M. Dm Waterworth, Thomas T. Scheffold, MIGen Consortium The, Suzanne S. van Dijk, Page Consortium The, Natasja M. Nm van Schoor, Changchun C. Xie, Nathalie van der Velde, Diana D. van Heemst, Anke Tönjes, Floor Va A. Fv van Oort, Anke Toenjes, David D. Siscovick, Daniel J Dj Rader, Rasheeda R. Williams, J. Wouter Jukema, John A Ja Spertus, Klaus K Stark, Qunyuan Qy Zhang, Kira K. Taylor, Pers Th, Stefan S Schreiber, Miguel M. Quibrera, Ulf U. de Faire, Henry Volzke, Hester M. Hm den Ruijter, Henry Voelzke, Tricia T. Thornton-Wells, Nicole N. Restrepo, Jason J. Umans, Sarah S. Wilson, Kylee K. Spencer, Hansong H. Wang, Ralph R. Shohet, Daniel D. Stram, Maarit M. Tiirikainen, Chunyuan C. Wu, Stephanie S. Rosse, LifeLines Cohort Study, Nigel W. Nw Rayner, Frida F. Renstrom, Neil R. Nr Robertson, Lynda M. Lm Rose, Ronan R. Roussel, Fr R. Schumacher, Serena S. Sanna

, Hubert H. Scharnagl, Salome S. Scholtens, Paul Iw W. Pi de Bakker, Heribert H. Schunkert, Robert A. Ra Scott, Joban J. Sehmi, Thomas T. Seufferlein, Jianxin J. Shi, Karri K. Silventoinen, Johannes H. Jh Smit, Albert Vernon AV Smith

, Joanna J. Smolonska, Alice V. Av Stanton

, Kathleen K. Stirrups, David J. Dj Stott, Heather M. Hm Stringham, Johan J. Sundström, Morris A. Swertz, Ann-Christine Ac Syvänen, Bamidele O. Bo Tayo, Suzanne Van Dijk, Gudmar G. Thorleifsson, Natasja M. Van Schoor

, Jonathan P. Jp Tyrer, N. Van Der Velde, Diana Van Heemst, Floor V. A. Van Oort, Pim P. van der Harst, Sita H. Sh Vermeulen, Niek N. Verweij

, Judith M. Jm Vonk, Pieter P. Zanen

, Lindsay L. Ll Waite, Melanie M. Waldenberger, Lr R. Wilkens, Roman R. Wennauer, Christina C. Willenborg, Tom T. Wilsgaard, Mary K. Mk Wojczynski, Andrew A. Wong, Alan F. Af Wright, Cornelia M. Cm van Duijn, Jackie F. Jf Price, Lu L. Qi, Olli T. Ot Raitakari, Tuomo T. Rankinen, Dc C. Dc Rao, Treva K. Tk Rice

, Marylyn D. Ritchie, Igor I. Rudan, Veikko Salomaa, Nilesh J. Nj Samani, Jouko J. Saramies, Mark A. Sarzynski, Peter Eh H. Pe Schwarz, Sylvain S. Sebert, Peter P. Sever, Alan R. Ar Shuldiner, Juha J. Sinisalo, Valgerdur Steinthorsdottir, Ronald P. Rp Stolk, Jean-Claude Jc Tardif, Anke A. Tönjes, Angelo A. Tremblay, Elena E. Tremoli, Jarmo J. Virtamo, Marie-Claude Mc Vohl, Frayling Tm, Louis L. Pérusse, Thomas T. Quertermous, Rainer R. Rauramaa, Eva E. Reinmaa, Paul M. Pm Ridker, Fernando F. Rivadeneira, Jerome I. Ji Rotter, Timo E. Te Saaristo, Danish D. Saleheen, David D. Schlessinger, Pe Eline PE Slagboom

, Harold H. Snieder, Pim Van Der Harst, Tim D. Td Spector, Konstantin K. Strauch, Michael M. Stumvoll, Jaakko J. Tuomilehto, Matti M. Uusitupa, Henry H. Völzke, Mark M. Walker, Nicholas J. Nj Wareham, Hugh H. Watkins, He-Erich He Wichmann, James F. Jf Wilson, Elizabeth K. Ek Speliotes, Unnur U. Thorsteinsdottir, David P. Dp Strachan, Cm M. Van Duijn, Kari K. Stefansson, André G. Ag Uitterlinden, Cristen J. Cj Willer, Michael N. Mn Weedon, Peter M. Pm Visscher, Tune H. Th Pers, Audrey Y. Ay Chu, Martin L. Ml Buchkovich, Tonu Tõnu Esko

, Damien C. Dc Croteau-Chonka, Felix R. Fr Day

, Anne U. Au Jackson, Ken Sin KS Lo, Adam E. Ae Locke

, Reedik R. Mägi, Eleonora Evelin Porcu, Evelin E. Mihailov, Peggy P. Peissig, Devin D. Absher, Eva E. Albrecht, Denise D. Anderson, Jeffrey J. Baron, Marian M. Beekman, Ayse Ayşe Demirkan, Georg Benedikt Gb Ehret, Stefan S. Gustafsson, Bjarke B. Feenstra, Mary F. Feitosa, Krista K. Fischer, Ross M. Rm Fraser, Anuj A. Goel, Jian J. Gong, Stavroula S. Kanoni, Marcus E. Me Kleber, Kati K. Kristiansson, Wood Ar, Unhee U. Lim, Justice A. E., Vaneet Lotay, Julian C. Jc Lui, Massimo M. Mangino, Dirkje S. Ds Postma, Karol K. Estrada, Carolina C. Medina-Gomez

, Michael A. Nalls, Dale R. Dr Nyholt

, Im M. Leach, Cameron D. Cd Palmer, Jian'An Jian’an Luan, Dorota D. Pasko, Sonali S. Pechlivanis

, Zoltán Zoltán Kutalik, Leena L. Peltonen, Flora F. Peyvandi, Najaf N. Amin, Anne E. Justice, Uzma U. Afzal, Alberto A. Piazza, Gillian M. Gm Arscott, Stefania S. Bandinelli, Amy A. Barrett, Claire C. Bellis, Amanda J. Aj Bennett, Christian C. Berne, Matthias M. Blüher, Jennifer L. Jl Bolton, Yvonne Y. Böttcher, Heather A. Ha Boyd, Marcel M. Bruinenberg, Leena L Peltonen, Brendan M. Bm Buckley, Michael M. Preuss, Steve Steven Buyske, Ida H. Ih Caspersen, Peter S. Ps Chines, Yanan Y. Duan, Robert R. Clarke, Simone S. Claudi-Boehm, Matthew M. Cooper, Ew Warwick EW Daw, Pim A. Pa De Jong, Joris J. Deelen

, Tove T. Fall, Graciela G. Delgado, Josh C. Jc Denny, Augusto D. Ad Pichard, Rosalie R. Dhonukshe-Rutten, Maria M. Dimitriou, Alex Sf F. As Doney, Marcus M. Dörr, Rudolf R. Fehrmann, Niina N. Eklund, Elodie E. Eury, Lasse L. Folkersen, Melissa E. Me Garcia, Frank F. Geller, Vilmantas Giedraitis, Alan S. As Go, Teresa T. Ferreira, Harald H. Grallert, Tanja B. Tb Grammer, Jürgen J. Gräßler, Henrik H. Grönberg, Christopher J. Cj Groves, Jeff Jeffrey Haessler, Per Hall, Lisette C. P. G. M. De Groot, Toomas T. Haller, Michael M Preuss, Goran Göran Hallmans, Anke A. Hannemann, Juha J. Karjalainen, Catharina A. Ca Hartman, Maija M. Hassinen, Louis Perusse, Caroline C. Hayward, Louis Pérusse, Nancy L. Nl Heard-Costa, Quinta Q. Helmer, Sharina S. Person, Gibran G. Hemani, Anjali K. Ak Henders

, Hans L. Hl Hillege, Mark A. Hlatky, Wolfgang W. Hoffmann, Per P. Hoffmann, Oddgeir O. Holmen, Jeanine J. Jj Houwing-Duistermaat, Sarah S. Pendergrass, Thomas T. Illig, Aaron A. Isaacs, Alan L. Al James, Janina Jarina Jeff, Berit Bent Johansen, Jennifer J. Jolley, Å. Johansson, Thorhildur T. Juliusdottir, Juhani J. Junttila, Ross R. Prentice, Abel N. Kho, Leena L. Kinnunen, Norman N. Klopp, Thomas T. Kocher, Audrey Y. Chun, Wolfgang W. Kratzer, Anne E. Ae, Peter P. Lichtner, Åsa Å Johansson, Lars L. Lind, Steven S. Buyske, Jaana J. Lindström, Reedik Mägi, Stéphane Stéphane Lobbens, Jeffrey J. Haessler, Mattias Matthias Lorentzon, Per P. Hall, Yingchang Yc Lu, Valeriya Lyssenko, Abel N. An Kho, Patrik Ke E. Pk Magnusson, Reedik Maegi, Anubha A. Mahajan, Justice Ae, Marc M. Maillard, Reedik Magi, Wendy L. Wl McArdle, Consortium Pagege, Colin A. Ca McKenzie, Yun Ju Sung, Stela S. McLachlan, Paul J. Pj McLaren, Catherine A. Ca McCarty, Cristina C. Menni, Åsa Johansson, Richard R. Berg, Sigrun S. Merger, Lili L. Milani, Alireza A. Moayyeri, James J. Linneman, Keri L. Kl Monda, Yvonne Böttcher, Mario A. Morken, Aaron A. Miller, Gabriele G. Müller, Martina M. Müller-Nurasyid, Anne E., Arthur W. Aw Musk, Vidhu Choudary, Narisu N. Narisu, Matthias M. Nauck, Ilja M. Im Nolte, Lin L. Chen, Markus M. Mm Nöthen, Stefan S. Pilz, Laticia L. Oozageer, Terrie T. Kitchner, Irene I. Mateo Leach, Norman N. Fost, Rex L. Rl Chisholm, Pedro C. Pc Avila, Philip P. Greenland, Chu Ay, Johan J. Arnl, Warren A. Wa Kibbe, Amy A. Aa Lemke, William L. Wl Lowe, Jennifer A. Ja Pacheco, Joel J. Humowiecki, Henrik Grönberg, Christopher C. Chute, May M. Law, Iftikar I. Kullo, Johan Arnloev, Barbara B. Koenig, Suzette S. Bielinski, Jyotishman J. Pathak, Joan J. Henriksen, Matthias Blueher, Keyue K. Ding, Yvonne Boettcher, Lacey L. Hart, Jeremy J. Palbicki, Eric B. Eb Larson, Katherine K. Newton, Evette E. Ludman, Gene G. Hart, David D. Carrell, Gail G. Jarvik, Paul P. Crane, Wylie W. Burke, Stephanie Malia SM Fullerton, Chris C. Carlson, Fred F. Hutchinson, Andrew A. McDavid, Marcus Dörr, Marcus Doerr, Ellen E. Clayton, Jonathan L. Jl Haines, Johan Arnlov, Daniel R. Dr Masys, Larry R. Lr Churchill, Daniel D. Cornfield, Dominique D. Arveiler, Jürgen Gräßler, Stephan Jl L. Sj Bakker, Juergen Graessler, John J. Beilby, Henrik Groenberg, Richard N. Bergman, Dana D. Crawford, Sven S. Bergmann, Colin A. Mckenzie, Reiner R. Biffar, Henrik Gronberg, John J. Blangero, Dawood D. Darbar, Dorret I. Di Boomsma, Stela Mclachlan, Stefan R. Bornstein, Bradley A. Malin, Pascal P. Bovet

, Joshua C. Jc Denny, Paolo P. Brambilla, Yvonne Bottcher, Morris J. Mj Brown, Gabriele Müller, Harry H. Campbell, Martina Müller-Nurasyid, Mark J. Mj Caulfield, Melissa M. Basford, Aravinda A. Chakravarti, Rory R. Collins, Behrooz Z. B. Alizadeh, Francis S. Fs Collins, H. Marike HM Boezen, Dana C. Dc Crawford, Gerjan G. Navis, La Adrienne LA Cupples, Johan J. Ormel, John J. Danesh, An N. Kho, Jaana Lindstroem, Ulf De Faire, Sekar S. Kathiresan, Hm M. Den Ruijter, Raimund R. Erbel, Diego D. Ardissino, Jeanette J. Erdmann, Kiran K. Musunuru, Johan G. Jg Eriksson, Pier M. Pm Mannucci, Martin M. Farrall, Sonia S. Anand, Ele E. Ferrannini, Jean J. Ferrières, James C. Jc Engert, Ian I. Ford, Gabriele Mueller, Nita G. Ng Forouhi, Thomas T. Morgan, Terrence T. Forrester, Martina Mueller-Nurasyid, Ron T. Rt Gansevoort, Abel An Kho, Pablo V. Pv Gejman, Domenico D. Girelli, Christian C. Gieger

, Alain A. Golay, Markus M. Noethen, Omri O. Gottesman, Pascal P. Pp McKeown, Vilmundur Gudnason, Ulf U. Gyllensten, Chris C. Cc Patterson, David W. Dw Haas, Gabriele Muller, Alistair S. As Hall, Markus Mm Nothen, Electronic Medical Records and Genomics (eMEMERGEGE) Consortium, Tamara B. Tb Harris, Andrew T. At Hattersley, Martina Muller-Nurasyid, Andrew C. Ac Heath, Christopher J. Cj O'Donnell, Christian C. Hengstenberg, Roberto R. Elosua, Andrew A. Aa Hicks, Olle O. Melander, Lucia A. La Hindorff, Aroon D. Ad Hingorani, Pier Angelica PA Merlini, Albert A. Hofman, David D. Altshuler, Gk Kees GK Hovingh, Carlo C. Berzuini, Steve E. Se Humphries, Sita H. Vermeulen, Steven C. Sc Hunt, Maurizio M. Ferrario, Elina E. Hypponen

, Luisa L. Bernardinelli, Kevin B. Kb Jacobs, Patrizia P. Celli, Marjo-Riitta Mr Jarvelin, Nicola N. Marziliano, Pekka P. Jousilahti, Raffaela R. Fetiveau, Antti M. Am Jula, Giorgio G. Casari, Jaakko J. Kaprio, Michele M. Galli, John Jp P. Jj Kastelein, Francesco F. Bernardi, Manfred M. Kayser, Frank F. Kee, Yechiel Y. Friedlander, Sirkka M. Sm Keinanen-Kiukaanniemi, Gavin G. Lucas, Lambertus A. La Kiemeney, Jaume J. Marrugat, Jaspal S. Js Kooner, James B. Jb Meigs, Charles C. Kooperberg, David M. Dm Nathan, Seppo S. Koskinen, Aki S. As Havulinna, Peter P. Kovacs, Aldi T. At Kraja, Stefano S. Duga, Meena M. Kumari, Calum A. Ca MacRae, Johanna J. Kuusisto, Goran G. Berglund, Timo A. Ta Lakka, Rosanna R. Asselta, Claudia C. Langenberg, Joshua M. Jm Korn, Loic L. Le Marchand, Terho T. Lehtimäki, James J. Nemesh, Sara S. Lupoli, Mark J. Mj Daly, Pamela Af F. Pa Madden, Satu S. Männistö, Diego D Ardissino, Paolo P. Manunta, Lauren L. Gianniny, André Andre Marette, Tara C. Tc Matise, Candace C. Guiducci, Barbara B. McKnight, Buchkovich Ml, Thomas T. Meitinger, Steven A. Sa McCarroll, Frans L. Fl Moll, Grant W. Gw Montgomery, Melissa M. Parkin, Andrew D. Ad Morris, Andrew P. Ap Morris, Jeffrey C. Jc Murray, Noel N. Burtt, Mari M. Nelis, Stacey B. Sb Gabriel, Claes C. Ohlsson, Albertine J. Aj Oldehinkel, Daniel D. Mirel, Ken K. Kk Ong, Peter S. Ps Braund, Willem H. Wh Ouwehand, Annette A. Peters, L. Adrienne Cupples, Gerard G. Pasterkamp, Le Marchandm Loic, Peter P. Pp Pramstaller

, Pier M Pm Mannucci, Roberto R Elosua, Anthony J. Aj Balmforth, Stephen G. Sg Ball, Sekar S Kathiresan, Patrick P. Linsel-Nitschke, Wolfgang W. Lieb, Christopher J Cj O'Donnell, Marcus M. Fischer, Olle O Melander, Inke R. Ir König, Croteau Chonka Dc, Anika A. Grosshennig, G. Kees Hovingh, Mg Geoffrey MG Hayes, Lo Ks, Kiran K Musunuru, Alison A. Goodall, Willem W. Ouwehand, Satu Männistö, Francois F. Cambien, Barbara Mcknight, Locke Ae, Gavin G Lucas, Loic Le Marchand, Zhen Z. Chen, Mingyao M. Li, Satu Mannisto, William W. Matthai, Philippe P. Amouyel, S. W. van der Laan, Folkert W. Fw Asselbergs, Hakon H. Hh Hakonarson, Themistocles L. Tl Assimes, Kenneth M. Km Kent, Murielle Murille Bochud, Joe J. Devaney, Bernhard O. Bo Boehm, Mary-Susan Burnett, Eric E. Boerwinkle, Christopher W. Cw Knouff, Erwin P. Ep Bottinger, Joseph M. Jm Lindsay, Claude C. Bouchard, Piw I. W. De Bakker, Stéphane Stephane Cauchi, Inke R. I. König, John C. Jc Chambers, Vincent Mooser, Stephen J. Sj Chanock, Richard S. Rs Cooper, Day Fr, George G. Dedoussis, Records The Electronic Medical, Consortium Genomics, Luigi L. Ferrucci, Mg Geoff M. Hayes, Paul W. Pw Franks, Stephen E. Se Epstein, Philippe P. Froguel, Study The LifeLines Cohort, Leif C. Lc Groop, Hilma H. Hólm, Christopher A. Ca Haiman, Ron R. Do, Anders A. Hamsten, Klaus K. Berger, Jennie J. Hui, David J. Dj Hunter, .., Kristian K. Hveem, Julia J. Higashio, Jw Wouter JW Jukema, Robert C. Rc Kaplan, Tara T. Matise, Mika M. Kivimaki, Jackson Au, Diana D. Kuh, Markku M. Laakso, Andrew A. Nato, Yongmei Ym Liu, Lucia L. Hindorff, Nicholas G. Ng Martin, Patrick P Linsel-Nitschke, Winfried W. März, Mads M. Melbye, Teri T. Manolio, Andreas A. Huge, Susanne S. Moebus, Patricia B. Pb Munroe, Wolfgang W Lieb, Inger I. Njølstad, Gerardo G. Heiss, Nancy L. Nl Pedersen, M. Geoffrey Hayes, Ben A. Oostra, Colin Na A. Cn Palmer, Marcus M Fischer, Markus M. Perola, Jose Luis JL Ambite, MIGen Consortium, Chris C Cc Patterson, Ulrike U. Peters, Pascal P Pp McKeown, Joseph E. Je Powell, Nora N. Franceschini, Chris C. Power, Anika A Grosshennig, Ewa E. Deelman, Winfried März, Nicola N. Martinelli, Roberto R. Corrocher, Winfried Marz, Oliviero O. Olivieri, Christy C. Avery, James C Jc Engert, Winfried Maerz, Danyu D. Lin, Sonia S Anand, P. Eline Slagboom, Misa M. Graff, Barbara B. Cochran, Jean J. MacCluer, Shelley S. Cole, James J. Pankow, David D Altshuler, Myron M. Gross, Nancy N. Jenny, Myriam M. Fornage, Alice A. Arnold, H. Erich Wichmann, Peter P. Durda, Bruce B. Patsy, Linda L. Kao, Deborah D. Murdock, Jonathan J. Haines, Kim K. Glenn, Petra P. Buzkova, William S. Ws Bush, Panos P. Deloukas

, Iris M. Im Heid, Jonathan J. Boston, Cecilia M. Cm Lindgren, Robert R. Goodloe, Jennifer J. Malinowski, Karen L. Kl Mohlke, Dana D Crawford, Matthew M. Oetjens, Jay J. Fowke, Inês Inês Barroso, P. A. de Jong, Caroline S. Cs Fox, Laurence L. Kolonel, Kari E. Ke North, Iona I. Cheng, Jacques S. Js Beckmann, Lani L. Park, Sonja I. Si Berndt, Logan L. Dumitrescu, Michael M. Boehnke, Ingrid B. Ib Borecki, Mark I. Mi McCarthy, Kristin K. Brown-Gentry, Christopher C. Haiman, Andres A. Metspalu, Sabrina L. Sl Mitchell, Brian B. Henderson, Kristine K. Monroe, Garnet G. Anderson, Andrea A. LaCroix, Lude L. Franke

, Chris C Carlson, Jeffrey R. O’connell, Alkes L. Al Price, Cara C. Carty, Jonathan J. Kocarnik, Guillaume G. Lettre, Ruth Jf F. Rj Loos, Yi Y. Lin, C. Elect Med Records & Genom eMERGE, Rebecca R. Jackson, Erik E. Ingelsson, Elect Med Records &amp, Jeffrey R. O'Connell, David D. Duggan, Goncalo R. Gr Abecasis, C. Genom eMERGE, Daniel I. Di Chasman, Consortium Page, Michael E. Me Goddard, Spertus Ja, Lew L. Kuller, Joel N. Jn Hirschhorn, Timothy M. Tm Frayling

, And Other, Others, Jackie Price

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Abstract

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated approximately 2,000, approximately 3,700 and approximately 9,500 SNPs explained approximately 21%, approximately 24% and approximately 29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes and pathways not highlighted in earlier efforts, such as signaling by fibroblast growth factors, WNT/beta-catenin and chondroitin sulfate-related genes. We identified several genes and pathways not previously connected with human skeletal growth, including mTOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number (thousands) of causal variants.

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Defining the role of common variation in the genomic and biological architecture of adult human height.

Abstract