Elsevier, Tetrahedron Letters, 8(40), p. 1597-1600
DOI: 10.1016/s0040-4039(98)02654-9
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The aromatic or aliphatic residue of native L-alpha-aminoacids is selectively included into the hydrophobic cavity of water soluble calix[4]arene receptors. The association constants values are determined by H-1 NMR titration experiments and the binding process is further elucidated by preliminary Molecular Mechanics calculations, which give results fully consistent with the NMR data