Elsevier, Separation and Purification Technology, 3(61), p. 266-275
DOI: 10.1016/j.seppur.2007.10.016
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Microwave-assisted extraction (MAE) was applied to the extraction of saikosaponin a, c and d from Radix Bupleuri. Several operating parameters, namely microwave power, time, temperature and ethanol concentration, were optimized using response surface methodology (RSM) with a central composite rotatable design (CCRD). The ethanol concentration and time were found to be the most significant factors (p